Y52B11A.4

Caenorhabditis elegans

Predicted to enable GTP binding activity and calcium channel regulator activity. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in congestive heart failure and type 2 diabetes mellitus. Is an ortholog of human REM1 (RRAD and GEM like GTPase 1); REM2 (RRAD and GEM like GTPase 2); and RRAD (RRAD, Ras related glycolysis inhibitor and calcium channel regulator).

F10E9.5

Caenorhabditis elegans

Predicted to be involved in spliceosomal snRNP assembly. Predicted to be part of SMN complex. Is an ortholog of human GEMIN8 (gem nuclear organelle associated protein 8).

Y67A10A.7

Caenorhabditis elegans

Predicted to be located in mitochondrion. Is an ortholog of several human genes including ARMCX1 (armadillo repeat containing X-linked 1); ARMCX2 (armadillo repeat containing X-linked 2); and ARMCX3 (armadillo repeat containing X-linked 3).

D1007.4

Caenorhabditis elegans

Predicted to be involved in spliceosomal snRNP assembly. Located in striated muscle dense body. Is an ortholog of human GEMIN6 (gem nuclear organelle associated protein 6).

C24H11.5

Caenorhabditis elegans

Predicted to be involved in spliceosomal snRNP assembly. Predicted to be part of Sm-like protein family complex. Is an ortholog of human GEMIN7 (gem nuclear organelle associated protein 7).

gem-4

Caenorhabditis elegans

Predicted to enable calcium-dependent phospholipid binding activity. Predicted to be involved in cellular response to calcium ion. Predicted to be located in plasma membrane. Expressed in several structures, including Z2; Z3; head mesodermal cell; hermaphrodite gonad; and somatic gonad precursor. Is an ortholog of human CPNE5 (copine 5) and CPNE9 (copine family member 9).

dpy-27

Caenorhabditis elegans

Enables sequence-specific DNA binding activity. Involved in dosage compensation by hypoactivation of X chromosome. Located in X chromosome and nuclear chromosome. Part of dosage compensation complex. Is an ortholog of human SMC4 (structural maintenance of chromosomes 4).

him-7

Caenorhabditis elegans

sdc-2

Caenorhabditis elegans

Involved in dosage compensation by hypoactivation of X chromosome and negative regulation of transcription by RNA polymerase II. Located in nuclear chromosome.

rec-1

Caenorhabditis elegans

Involved in meiotic DNA double-strand break formation involved in reciprocal meiotic recombination.