gdi-1

Caenorhabditis elegans

Predicted to enable Rab GDP-dissociation inhibitor activity. Predicted to be involved in vesicle-mediated transport. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in Down syndrome; non-syndromic X-linked intellectual disability 41; and psychotic disorder. Is an ortholog of human GDI1 (GDP dissociation inhibitor 1) and GDI2 (GDP dissociation inhibitor 2).

rhi-1

Caenorhabditis elegans

Predicted to enable Rho GDP-dissociation inhibitor activity. Predicted to be involved in Rho protein signal transduction. Located in cytosol and membrane. Human ortholog(s) of this gene implicated in nephrotic syndrome type 8. Is an ortholog of human ARHGDIA (Rho GDP dissociation inhibitor alpha); ARHGDIB (Rho GDP dissociation inhibitor beta); and ARHGDIG (Rho GDP dissociation inhibitor gamma).

gna-1

Caenorhabditis elegans

Predicted to enable glucosamine 6-phosphate N-acetyltransferase activity. Predicted to be involved in UDP-N-acetylglucosamine biosynthetic process. Is an ortholog of human GNPNAT1 (glucosamine-phosphate N-acetyltransferase 1).

png-1

Caenorhabditis elegans

Enables peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity and protein-disulfide reductase (NAD(P)H) activity. Involved in ERAD pathway; cell redox homeostasis; and negative regulation of collateral sprouting. Located in cytoplasm. Expressed in body wall musculature; gonad; neurons; pharynx; and vulva. Human ortholog(s) of this gene implicated in NGLY1-deficiency. Is an ortholog of human NGLY1 (N-glycanase 1).