gcy-23

Caenorhabditis elegans

Predicted to enable adenylate cyclase activity; guanylate cyclase activity; and peptide receptor activity. Involved in detection of temperature stimulus; thermosensory behavior; and thermotaxis. Located in neuron projection terminus. Expressed in AFDL and AFDR.

gcy-8

Caenorhabditis elegans

Enables guanylate cyclase activity. Involved in microvillus organization and response to temperature stimulus. Located in microvillus membrane and neuron projection terminus. Expressed in AFDL and AFDR.

gcy-18

Caenorhabditis elegans

Predicted to enable adenylate cyclase activity; guanylate cyclase activity; and peptide receptor activity. Involved in detection of temperature stimulus; thermosensory behavior; and thermotaxis. Located in microvillus membrane and neuron projection terminus. Expressed in intestine and nervous system.

gcy-2

Caenorhabditis elegans

Expressed in PVT and head neurons.

gcy-28

Caenorhabditis elegans

Enables guanylate cyclase activity. Involved in chemotaxis; olfactory behavior; and sensory perception. Located in cell body and neuron projection. Expressed in body wall musculature; gonad; hypodermis; intestine; and neurons. Human ortholog(s) of this gene implicated in artery disease (multiple) and bone development disease (multiple). Is an ortholog of human NPR1 (natriuretic peptide receptor 1).

tbc-3

Caenorhabditis elegans

Predicted to enable GTPase activator activity. Located in Golgi apparatus. Expressed in hermaphrodite distal tip cell; neurons; pharynx; rect_D; and seam cell. Is an ortholog of human TBC1D22A (TBC1 domain family member 22A) and TBC1D22B (TBC1 domain family member 22B).

gcy-4

Caenorhabditis elegans

Predicted to enable adenylate cyclase activity; guanylate cyclase activity; and peptide receptor activity. Involved in chemosensory behavior; chemotaxis; and response to salt. Predicted to be located in plasma membrane. Expressed in ASER.

gcy-19

Caenorhabditis elegans

Predicted to enable guanylate cyclase activity and protein kinase activity. Predicted to be involved in cGMP biosynthetic process and intracellular signal transduction. Predicted to be located in membrane. Expressed in inner labial neurons and nervous system.

gcy-37

Caenorhabditis elegans

Predicted to enable guanylate cyclase activity. Predicted to be involved in cGMP-mediated signaling and response to oxygen levels. Predicted to be located in cytoplasm. Predicted to be part of guanylate cyclase complex, soluble. Is an ortholog of human GUCY1B2 (guanylate cyclase 1 soluble subunit beta 2 (pseudogene)).

gcy-34

Caenorhabditis elegans

Predicted to enable guanylate cyclase activity. Involved in chemosensory behavior and sensory perception of bitter taste. Predicted to be located in cytoplasm. Predicted to be part of guanylate cyclase complex, soluble. Human ortholog(s) of this gene implicated in Alzheimer's disease. Is an ortholog of human GUCY1B2 (guanylate cyclase 1 soluble subunit beta 2 (pseudogene)).