gar-1

Caenorhabditis elegans

Enables G protein-coupled acetylcholine receptor activity. Involved in cholinergic synaptic transmission. Located in postsynaptic membrane. Expressed in PVM and head neurons.

gar-2

Caenorhabditis elegans

Enables G protein-coupled acetylcholine receptor activity. Involved in G protein-coupled receptor signaling pathway; negative regulation of cholinergic synaptic transmission; and response to xenobiotic stimulus. Located in axon. Expressed in neurons.

ZK856.5

Caenorhabditis elegans

Predicted to enable phosphoric diester hydrolase activity. Predicted to be located in extracellular space. Is an ortholog of human SMPDL3B (sphingomyelin phosphodiesterase acid like 3B).

gar-3

Caenorhabditis elegans

Enables G protein-coupled acetylcholine receptor activity. Involved in several processes, including G protein-coupled acetylcholine receptor signaling pathway; positive regulation of acetylcholine secretion, neurotransmission; and positive regulation of protein localization to synapse. Located in plasma membrane. Expressed in body wall musculature; linker cell; neurons; non-striated muscle; and somatic nervous system. Human ortholog(s) of this gene implicated in several diseases, including Chagas disease; autoimmune disease of the nervous system (multiple); and lung disease (multiple). Is an ortholog of human CHRM1 (cholinergic receptor muscarinic 1); CHRM3 (cholinergic receptor muscarinic 3); and CHRM5 (cholinergic receptor muscarinic 5).

prel-3

Caenorhabditis elegans

Predicted to enable phosphatidic acid transfer activity. Predicted to be involved in phospholipid transport. Predicted to be located in mitochondrial intermembrane space. Is an ortholog of human PRELID3B (PRELI domain containing 3B).

C44H4.4

Caenorhabditis elegans

Expressed in head. Is an ortholog of human BLTP3A (bridge-like lipid transfer protein family member 3A) and BLTP3B (bridge-like lipid transfer protein family member 3B). Human BLTP3B enables GARP complex binding activity; lipid transfer activity; and protein homodimerization activity.

sftb-6

Caenorhabditis elegans

Predicted to enable RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of U2 snRNP and spliceosomal complex. Is an ortholog of human SF3B6 (splicing factor 3b subunit 6).

teg-4

Caenorhabditis elegans

Predicted to enable U2 snRNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of U2 snRNP. Is an ortholog of human SF3B3 (splicing factor 3b subunit 3).

H18N23.2

Caenorhabditis elegans

Predicted to enable glycogen binding activity and protein phosphatase 1 binding activity. Predicted to be involved in regulation of glycogen biosynthetic process. Predicted to be part of protein phosphatase type 1 complex. Is an ortholog of human PPP1R3B (protein phosphatase 1 regulatory subunit 3B).

sftb-2

Caenorhabditis elegans

Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of U2 snRNP and spliceosomal complex. Expressed in head and tail. Human ortholog(s) of this gene implicated in Goldenhar syndrome. Is an ortholog of human SF3B2 (splicing factor 3b subunit 2).