Involved in non-motile cilium assembly. Located in ciliary basal body and dendrite. Expressed in ciliated neurons. Is an ortholog of human FBF1 (Fas binding factor 1).
Predicted to be involved in negative regulation of extrinsic apoptotic signaling pathway via death domain receptors. Is an ortholog of human FAIM (Fas apoptotic inhibitory molecule).
Predicted to enable fatty acid synthase activity. Predicted to be involved in fatty acid biosynthetic process. Expressed in excretory duct; hermaphrodite gonad; hypodermis; intestine; and neurons. Used to study muscular disease. Human ortholog(s) of this gene implicated in colorectal cancer. Is an ortholog of human FASN (fatty acid synthase).
Predicted to enable ubiquitin binding activity. Predicted to be involved in ERAD pathway. Predicted to be located in endoplasmic reticulum and nucleus. Expressed in intestinal cell. Is an ortholog of human FAF1 (Fas associated factor 1).
Enables K48-linked polyubiquitin modification-dependent protein binding activity. Involved in several processes, including developmental process involved in reproduction; positive regulation of mitotic cell cycle, embryonic; and regulation of protein localization to chromatin. Located in nucleus and perinuclear region of cytoplasm. Part of chromatin. Expressed in gonad; neurons; spermatheca; and spermatocyte. Is an ortholog of human FAF1 (Fas associated factor 1).
Predicted to be involved in negative regulation of apoptotic signaling pathway. Predicted to be located in Golgi apparatus; endoplasmic reticulum; and membrane. Expressed in excretory system; neurons; and pharyngeal muscle cell. Is an ortholog of human GRINA (glutamate ionotropic receptor NMDA type subunit associated protein 1).
Enables nuclear receptor binding activity and transcription coactivator activity. Involved in several processes, including determination of adult lifespan; regulation of primary metabolic process; and sequestering of triglyceride. Predicted to be located in nucleus. Expressed in head. Used to study chromosome 22q11.2 deletion syndrome, distal. Human ortholog(s) of this gene implicated in schizophrenia. Is an ortholog of human MED15 (mediator complex subunit 15).