ets-8

Caenorhabditis elegans

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is an ortholog of human ETV1 (ETS variant transcription factor 1); ETV4 (ETS variant transcription factor 4); and ETV5 (ETS variant transcription factor 5).

elf-1

Caenorhabditis elegans

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in gonad development and regulation of cell division. Predicted to be located in nucleus. Expressed in head neurons and pharynx. Is an ortholog of human ELF1 (E74 like ETS transcription factor 1); ELF2 (E74 like ETS transcription factor 2); and ELF4 (E74 like ETS transcription factor 4).

svh-5

Caenorhabditis elegans

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in intestine and neurons. Is an ortholog of human EHF (ETS homologous factor); ELF3 (E74 like ETS transcription factor 3); and ELF5 (E74 like ETS transcription factor 5).

ets-9

Caenorhabditis elegans

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in diabetes mellitus (multiple); hematologic cancer (multiple); and thrombocytopenia. Is an ortholog of several human genes including ETS1 (ETS proto-oncogene 1, transcription factor); ETS2 (ETS proto-oncogene 2, transcription factor); and ETV6 (ETS variant transcription factor 6).

C52B9.19

Caenorhabditis elegans

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in diabetes mellitus (multiple); hematologic cancer (multiple); and thrombocytopenia. Is an ortholog of several human genes including ETS1 (ETS proto-oncogene 1, transcription factor); ETS2 (ETS proto-oncogene 2, transcription factor); and ETV6 (ETS variant transcription factor 6).

thn-7

Caenorhabditis elegans

Is affected by cyc-1; ets-4; and eat-2 based on microarray studies. Is affected by methylmercuric chloride and multi-walled carbon nanotube based on microarray and RNA-seq studies.

F26D10.13

Caenorhabditis elegans

Enriched in male based on RNA-seq studies. Is affected by several genes including qui-1; ets-4; and csr-1 based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including allantoin; Sirolimus; and metformin based on RNA-seq studies.

Y53F4B.8

Caenorhabditis elegans

Is affected by several genes including cyc-1; swsn-2.2; and ets-4 based on microarray and RNA-seq studies. Is affected by ten chemicals including Mercuric Chloride; rotenone; and Sodium Chloride based on microarray and RNA-seq studies.

lin-1

Caenorhabditis elegans

Enables sequence-specific DNA binding activity. Contributes to RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including egg-laying behavior; negative regulation of transcription by RNA polymerase II; and vulval development. Located in nucleus. Part of RNA polymerase II transcription repressor complex. Expressed in vulval precursor cell. Human ortholog(s) of this gene implicated in Alzheimer's disease; Huntington's disease; Lewy body dementia; and schizophrenia. Is an ortholog of human ELK1 (ETS transcription factor ELK1).

srbc-15

Caenorhabditis elegans

Enriched in CEPshDL; CEPsoDL; CEPsoVL; and NSM based on tiling array and single-cell RNA-seq studies. Is affected by several genes including ets-4; rsr-2; and lsm-1 based on microarray; tiling array; and RNA-seq studies. Is affected by resveratrol based on microarray studies.