dcr-1

Caenorhabditis elegans

Enables deoxyribonuclease I activity and ribonuclease III activity. Involved in several processes, including nucleobase-containing compound catabolic process; olfactory learning; and regulatory ncRNA-mediated gene silencing. Acts upstream of or within defense response to Gram-positive bacterium. Located in cytosol and nucleus. Expressed in germ line; intestine; neurons; and somatic cell. Human ortholog(s) of this gene implicated in several diseases, including DICER1 syndrome; gastrointestinal system cancer (multiple); and multinodular goiter. Is an ortholog of human DICER1 (dicer 1, ribonuclease III).

srt-71

Caenorhabditis elegans

Is affected by mir-34; eri-1; and let-60 based on microarray studies.

eri-1

Caenorhabditis elegans

Enables 3'-5'-RNA exonuclease activity. Involved in RNA metabolic process; regulation of gene expression; and sexual reproduction. Located in cytoplasm. Expressed in neurons and spermatheca. Is an ortholog of human ERI1 (exoribonuclease 1).

str-223

Caenorhabditis elegans

Is affected by hpl-2; sftb-1; and eri-1 based on tiling array; RNA-seq; and microarray studies.

srx-109

Caenorhabditis elegans

Is affected by clk-1; etr-1; and eri-1 based on microarray and RNA-seq studies. Is affected by Sirolimus based on microarray studies.

srh-307

Caenorhabditis elegans

Enriched in ASJ; PVS; and muscle cell based on single-cell RNA-seq and microarray studies. Is affected by several genes including etr-1; eri-1; and glh-4 based on RNA-seq and microarray studies. Is affected by six chemicals including rifampin; Psoralens; and Sirolimus based on RNA-seq and microarray studies.

D1044.4

Caenorhabditis elegans

Is affected by several genes including eri-1; hpl-2; and clk-1 based on tiling array and microarray studies. Is affected by resveratrol based on microarray studies.

T02H6.10

Caenorhabditis elegans

Is affected by rsr-2; eat-2; and eri-1 based on tiling array; RNA-seq; and microarray studies. Is affected by tryptophan; Atrazine; and Sirolimus based on microarray studies.

C02B4.3

Caenorhabditis elegans

Is affected by several genes including etr-1; eri-1; and egl-43 based on tiling array; RNA-seq; and microarray studies. Is affected by Atrazine; fluoranthene; and paraquat based on microarray studies.

F53C3.7

Caenorhabditis elegans

Enriched in several structures, including AVK; MSpppaaa; head mesodermal cell; male distal tip cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eri-1; hpk-1; and glh-4 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including metformin; Psoralens; and allantoin based on RNA-seq and microarray studies.