Predicted to enable protein kinase regulator activity. Predicted to be involved in mitophagy; piecemeal microautophagy of the nucleus; and protein localization to phagophore assembly site. Predicted to be located in autophagosome; cytosol; and phagophore assembly site. Predicted to be part of Atg1/ULK1 kinase complex. Expressed in body wall musculature; nerve ring; neurons; and pharyngeal muscle cell. Is an ortholog of human ATG13 (autophagy related 13).
Predicted to enable phosphatidylinositol 3-kinase regulator activity and protein-membrane adaptor activity. Involved in macroautophagy; positive regulation of autophagy; and positive regulation of embryonic development. Located in cytoplasm. Expressed in neurons and pharyngeal muscle cell.
Enables phosphatidylinositol phosphate binding activity. Involved in autophagosome assembly. Located in cytoplasm. Expressed widely. Human ortholog(s) of this gene implicated in neurodegeneration with brain iron accumulation 5. Is an ortholog of human WDR45 (WD repeat domain 45).
Enables protein kinase binding activity. Involved in aggrephagy. Predicted to be located in phagophore assembly site. Predicted to be part of Atg1/ULK1 kinase complex. Expressed in several structures, including body wall musculature; head; hypodermis; pharyngeal muscle cell; and tail. Human ortholog(s) of this gene implicated in cholangiocarcinoma; colon cancer; and hepatocellular carcinoma. Is an ortholog of human ATG101 (autophagy related 101).