dpr-1

Caenorhabditis elegans

Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus.

end-3

Caenorhabditis elegans

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in endodermal cell fate specification and mesodermal cell fate specification. Located in nucleus. Expressed in E; E lineage cell; Ea; Ep; and intestine.

ints-2

Caenorhabditis elegans

Predicted to be involved in snRNA 3'-end processing. Predicted to be part of integrator complex. Is an ortholog of human INTS2 (integrator complex subunit 2).

cids-2

Caenorhabditis elegans

Predicted to enable RNA polymerase II complex binding activity. Involved in mRNA 3'-end processing. Is an ortholog of human RPRD2 (regulation of nuclear pre-mRNA domain containing 2).

end-1

Caenorhabditis elegans

Enables DNA-binding transcription activator activity, RNA polymerase II-specific. Involved in endodermal cell fate specification and positive regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in E; E lineage cell; Ea; and Ep.

cpf-2

Caenorhabditis elegans

Predicted to enable mRNA binding activity. Predicted to be involved in mRNA 3'-end processing. Located in nuclear speck. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability. Is an ortholog of human CSTF2 (cleavage stimulation factor subunit 2) and CSTF2T (cleavage stimulation factor subunit 2 tau variant).

dhs-6

Caenorhabditis elegans

Predicted to enable oxidoreductase activity. Predicted to be located in mitochondrion. Is an ortholog of human HSDL2 (hydroxysteroid dehydrogenase like 2).

ptrn-1

Caenorhabditis elegans

Enables microtubule minus-end binding activity. Involved in cytoplasmic microtubule organization and nematode larval development. Located in microtubule minus-end. Expressed in hypodermis; intestine; nervous system; and pharynx. Human ortholog(s) of this gene implicated in complex cortical dysplasia with other brain malformations. Is an ortholog of human CAMSAP1 (calmodulin regulated spectrin associated protein 1); CAMSAP2 (calmodulin regulated spectrin associated protein family member 2); and CAMSAP3 (calmodulin regulated spectrin associated protein family member 3).

T08D2.8

Caenorhabditis elegans

Predicted to enable microtubule plus end polymerase and microtubule plus-end binding activity. Predicted to be involved in establishment or maintenance of microtubule cytoskeleton polarity; microtubule polymerization; and spindle organization. Predicted to be located in intracellular non-membrane-bounded organelle and supramolecular complex.

ebp-3

Caenorhabditis elegans

Predicted to enable microtubule plus-end binding activity. Predicted to be involved in protein localization to microtubule; regulation of microtubule polymerization or depolymerization; and spindle assembly. Predicted to be located in microtubule cytoskeleton. Human ortholog(s) of this gene implicated in congenital symmetric circumferential skin creases 2. Is an ortholog of human MAPRE1 (microtubule associated protein RP/EB family member 1); MAPRE2 (microtubule associated protein RP/EB family member 2); and MAPRE3 (microtubule associated protein RP/EB family member 3).