egl-45

Caenorhabditis elegans

Predicted to enable mRNA binding activity and translation regulator activity. Predicted to contribute to translation initiation factor activity. Involved in egg-laying behavior and embryo development. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic translation initiation factor 3 complex, eIF3e; eukaryotic translation initiation factor 3 complex, eIF3m; and multi-eIF complex. Expressed in neurons. Is an ortholog of human EIF3A (eukaryotic translation initiation factor 3 subunit A).

eif-3.I

Caenorhabditis elegans

Predicted to enable RNA binding activity and translation initiation factor activity. Predicted to be involved in cytoplasmic translational initiation. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic translation initiation factor 3 complex, eIF3m. Is an ortholog of human EIF3I (eukaryotic translation initiation factor 3 subunit I).

eif-3.J

Caenorhabditis elegans

Predicted to enable translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic translation initiation factor 3 complex. Is an ortholog of human EIF3J (eukaryotic translation initiation factor 3 subunit J).

eif-3.K

Caenorhabditis elegans

Predicted to enable RNA binding activity and ribosome binding activity. Predicted to contribute to translation initiation factor activity. Involved in positive regulation of apoptotic process. Located in cytoplasm. Expressed in several structures, including embryonic cell and germ line. Is an ortholog of human EIF3K (eukaryotic translation initiation factor 3 subunit K).

eif-3.C

Caenorhabditis elegans

Predicted to enable translation initiation factor binding activity. Predicted to contribute to translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic translation initiation factor 3 complex. Is an ortholog of human EIF3C (eukaryotic translation initiation factor 3 subunit C) and EIF3CL (eukaryotic translation initiation factor 3 subunit C like).

eif-3.D

Caenorhabditis elegans

Predicted to enable translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic translation initiation factor 3 complex. Expressed in pharynx. Is an ortholog of human EIF3D (eukaryotic translation initiation factor 3 subunit D).

eif-3.F

Caenorhabditis elegans

Predicted to enable translation initiation factor binding activity. Predicted to contribute to translation initiation factor activity. Involved in translation. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic translation initiation factor 3 complex, eIF3m. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 67. Is an ortholog of human EIF3F (eukaryotic translation initiation factor 3 subunit F).

eif-3.H

Caenorhabditis elegans

Predicted to enable metallopeptidase activity. Predicted to contribute to translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic 43S preinitiation complex and eukaryotic translation initiation factor 3 complex. Human ortholog(s) of this gene implicated in breast cancer and prostate carcinoma. Is an ortholog of human EIF3H (eukaryotic translation initiation factor 3 subunit H).

eif-3.E

Caenorhabditis elegans

Predicted to enable translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to be located in nucleus. Predicted to be part of eukaryotic translation initiation factor 3 complex. Expressed in head and tail. Is an ortholog of human EIF3E (eukaryotic translation initiation factor 3 subunit E).

eif-3.L

Caenorhabditis elegans

Predicted to enable translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic translation initiation factor 3 complex. Expressed in head and tail. Is an ortholog of human EIF3L (eukaryotic translation initiation factor 3 subunit L).