efn-3

Caenorhabditis elegans

Predicted to enable ephrin receptor binding activity. Predicted to be involved in axon guidance and ephrin receptor signaling pathway. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in craniofrontonasal syndrome; dysostosis; and stomach cancer. Is an ortholog of human EFNB1 (ephrin B1).

efn-4

Caenorhabditis elegans

Predicted to enable ephrin receptor binding activity. Involved in several processes, including embryonic morphogenesis; nematode male tail tip morphogenesis; and regulation of axon guidance. Located in axon and neuronal cell body. Expressed in several structures, including CAN; epithelial cell; ganglia; intestinal cell; and somatic nervous system. Human ortholog(s) of this gene implicated in craniofrontonasal syndrome; dysostosis; and stomach cancer. Is an ortholog of human EFNB1 (ephrin B1).

wrk-1

Caenorhabditis elegans

Predicted to enable axon guidance receptor activity. Predicted to be involved in homophilic cell adhesion via plasma membrane adhesion molecules and synapse organization. Predicted to be located in axon; neuronal cell body; and plasma membrane. Expressed in several structures, including SMDVL; body ganglion; head neurons; hermaphrodite distal tip cell; and interfacial epithelial cell.

plx-2

Caenorhabditis elegans

Enables semaphorin receptor activity. Involved in several processes, including axonal fasciculation; nematode larval development; and nematode male tail tip morphogenesis. Located in cell leading edge and cell surface. Expressed in several structures, including P3/4L; P9/10L; P9/10R; neuroblasts; and ray structural cell.

ptp-3

Caenorhabditis elegans

Enables protein tyrosine phosphatase activity. Involved in several processes, including embryonic morphogenesis; nervous system development; and neuroblast migration. Located in adherens junction and synapse. Expressed in embryonic cell; hypodermis; and nervous system. Human ortholog(s) of this gene implicated in artery disease (multiple); glucose metabolism disease (multiple); and obesity. Is an ortholog of human PTPRD (protein tyrosine phosphatase receptor type D) and PTPRF (protein tyrosine phosphatase receptor type F).