- dkf-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables protein serine/threonine kinase activity. Involved in several processes, including defense response to Gram-positive bacterium; determination of adult lifespan; and positive regulation of protein import into nucleus. Acts upstream of or within with a positive effect on neuromuscular synaptic transmission. Located in several cellular components, including axon; cell cortex; and somatodendritic compartment. Expressed in neurons.
- dkf-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables protein homodimerization activity and protein serine/threonine kinase activity. Involved in defense response to bacterium; determination of adult lifespan; and signal transduction. Acts upstream of with a negative effect on protein import into nucleus. Located in cytoplasmic side of plasma membrane and cytosol. Part of serine/threonine protein kinase complex. Expressed in AVF; NSM; head neurons; lumbar neurons; and spermathecal-uterine junction. Human ortholog(s) of this gene implicated in congenital heart disease. Is an ortholog of human PRKD1 (protein kinase D1); PRKD2 (protein kinase D2); and PRKD3 (protein kinase D3).
- tra-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables transmembrane signaling receptor activity. Involved in developmental process involved in reproduction and oocyte fate determination. Located in nucleus; perinuclear region of cytoplasm; and plasma membrane. Expressed in germ line.
- metl-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable tRNA (cytidine-3-)-methyltransferase activity. Predicted to be involved in methylation. Is an ortholog of human METTL2A (methyltransferase 2A, tRNA N3-cytidine) and METTL2B (methyltransferase 2B, tRNA N3-cytidine).
- R53.5 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable antioxidant activity. Predicted to be involved in cellular oxidant detoxification. Predicted to be located in cytoplasm. Expressed in hypodermis; muscle cell; and ventral nerve cord. Is an ortholog of human PRXL2A (peroxiredoxin like 2A).
- vps-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to be involved in endosome transport via multivesicular body sorting pathway; late endosome to vacuole transport; and protein transport. Located in cytoplasm. Expressed in tail. Is an ortholog of human CHMP2A (charged multivesicular body protein 2A).