ZK856.5

Caenorhabditis elegans

Predicted to enable phosphoric diester hydrolase activity. Predicted to be located in extracellular space. Is an ortholog of human SMPDL3B (sphingomyelin phosphodiesterase acid like 3B).

prel-3

Caenorhabditis elegans

Predicted to enable phosphatidic acid transfer activity. Predicted to be involved in phospholipid transport. Predicted to be located in mitochondrial intermembrane space. Is an ortholog of human PRELID3B (PRELI domain containing 3B).

C44H4.4

Caenorhabditis elegans

Expressed in head. Is an ortholog of human BLTP3A (bridge-like lipid transfer protein family member 3A) and BLTP3B (bridge-like lipid transfer protein family member 3B). Human BLTP3B enables GARP complex binding activity; lipid transfer activity; and protein homodimerization activity.

sftb-6

Caenorhabditis elegans

Predicted to enable RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of U2 snRNP and spliceosomal complex. Is an ortholog of human SF3B6 (splicing factor 3b subunit 6).

teg-4

Caenorhabditis elegans

Predicted to enable U2 snRNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of U2 snRNP. Is an ortholog of human SF3B3 (splicing factor 3b subunit 3).

H18N23.2

Caenorhabditis elegans

Predicted to enable glycogen binding activity and protein phosphatase 1 binding activity. Predicted to be involved in regulation of glycogen biosynthetic process. Predicted to be part of protein phosphatase type 1 complex. Is an ortholog of human PPP1R3B (protein phosphatase 1 regulatory subunit 3B).

sftb-2

Caenorhabditis elegans

Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of U2 snRNP and spliceosomal complex. Expressed in head and tail. Human ortholog(s) of this gene implicated in Goldenhar syndrome. Is an ortholog of human SF3B2 (splicing factor 3b subunit 2).

C34F6.10

Caenorhabditis elegans

Predicted to be involved in axon guidance; cell-cell adhesion; and neuron migration. Predicted to be located in axonal growth cone; cell surface; and plasma membrane. Expressed in RIH and body wall musculature. Is an ortholog of human FNDC3A (fibronectin type III domain containing 3A) and FNDC3B (fibronectin type III domain containing 3B).

prx-12

Caenorhabditis elegans

Predicted to enable ubiquitin-protein transferase activity. Involved in nematode larval development and peroxisome organization. Predicted to be located in peroxisomal membrane. Predicted to be part of peroxisomal importomer complex. Human ortholog(s) of this gene implicated in peroxisome biogenesis disorder 3A and peroxisome biogenesis disorder 3B. Is an ortholog of human PEX12 (peroxisomal biogenesis factor 12).

sftb-1

Caenorhabditis elegans

Predicted to enable mRNA binding activity. Involved in negative regulation of gene expression. Predicted to be located in nucleus. Predicted to be part of U2 snRNP; U2-type prespliceosome; and catalytic step 2 spliceosome. Human ortholog(s) of this gene implicated in hepatocellular carcinoma and myelodysplastic syndrome. Is an ortholog of human SF3B1 (splicing factor 3b subunit 1).