mrpl-30

Caenorhabditis elegans

Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in mitochondrion. Predicted to be part of large ribosomal subunit. Is an ortholog of human MRPL30 (mitochondrial ribosomal protein L30).

dylt-1

Caenorhabditis elegans

Predicted to enable dynein intermediate chain binding activity. Predicted to be involved in microtubule-based movement. Predicted to be located in cytoplasm. Predicted to be part of cytoplasmic dynein complex. Expressed in ADFL and ADFR. Is an ortholog of human DYNLT1 (dynein light chain Tctex-type 1) and DYNLT3 (dynein light chain Tctex-type 3).

dyrb-1

Caenorhabditis elegans

Predicted to enable dynein intermediate chain binding activity. Predicted to be involved in microtubule-based movement. Located in several cellular components, including cell cortex; microtubule cytoskeleton; and perinuclear region of cytoplasm. Expressed in ciliated neurons and intestine. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Is an ortholog of human DYNLRB1 (dynein light chain roadblock-type 1) and DYNLRB2 (dynein light chain roadblock-type 2).

cfim-1

Caenorhabditis elegans

Enables identical protein binding activity. Predicted to be involved in mRNA processing. Predicted to be located in cytoplasm and nucleus. Predicted to be part of mRNA cleavage factor complex. Is an ortholog of human NUDT21 (nudix hydrolase 21).

K04F10.3

Caenorhabditis elegans

Enriched in several structures, including ABalppppaa; ABpraaapaa; excretory cell; germ line; and interneuron based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including cyc-1; atfs-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including Tunicamycin; manganese chloride; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site.

chd-1

Caenorhabditis elegans

Predicted to enable several functions, including ATP hydrolysis activity; ATP-dependent chromatin remodeler activity; and histone binding activity. Predicted to be involved in nucleosome organization. Predicted to be located in nucleus. Predicted to be part of chromatin. Expressed in several structures, including germ cell and somatic cell. Human ortholog(s) of this gene implicated in castration-resistant prostate carcinoma and developmental and epileptic encephalopathy 94. Is an ortholog of human CHD1 (chromodomain helicase DNA binding protein 1).

npp-22

Caenorhabditis elegans

Predicted to enable protein-macromolecule adaptor activity. Predicted to be involved in nuclear pore organization. Part of nuclear pore. Is an ortholog of human NDC1 (NDC1 transmembrane nucleoporin).

dhc-1

Caenorhabditis elegans

Predicted to enable dynein intermediate chain binding activity; dynein light intermediate chain binding activity; and minus-end-directed microtubule motor activity. Involved in several processes, including neuron remodeling; organelle localization; and regulation of cellular localization. Located in several cellular components, including kinetochore; nuclear envelope; and spindle pole. Expressed in germ cell; head; somatic cell; and tail. Used to study epilepsy and lissencephaly. Human ortholog(s) of this gene implicated in Alzheimer's disease; Charcot-Marie-Tooth disease axonal type 2O; autosomal dominant intellectual developmental disorder 13; and spinal muscular atrophy with lower extremity predominant 1. Is an ortholog of human DYNC1H1 (dynein cytoplasmic 1 heavy chain 1).

mop-25.2

Caenorhabditis elegans

Predicted to enable protein serine/threonine kinase activator activity. Involved in asymmetric neuroblast division. Predicted to be located in cytoplasm and spindle pole. Human ortholog(s) of this gene implicated in hepatocellular carcinoma and pancreatic cancer. Is an ortholog of human CAB39 (calcium binding protein 39) and CAB39L (calcium binding protein 39 like).

efa-6

Caenorhabditis elegans

Predicted to enable guanyl-nucleotide exchange factor activity. Involved in several processes, including mitotic nuclear membrane disassembly; regulation of cellular component organization; and regulation of mitotic centrosome separation. Located in cell cortex; microtubule minus-end; and plasma membrane. Expressed in U.la; U.lp; and linker cell. Is an ortholog of human PSD (pleckstrin and Sec7 domain containing).