Zfp746

Mus musculus

PHENOTYPE: Mice homozygous for a null allele show decreased incidence of DEN-induced liver tumors. [provided by MGI curators]

Mgat3

Mus musculus

PHENOTYPE: Mice homozygous for a null allele exhibit reduced DEN and PB-induced hepatic tumors and reduced hepatocyte proliferation. [provided by MGI curators]

Acot12

Mus musculus

PHENOTYPE: Mice homozygous for a null allele exhibit accelerated liver tumor formation in DEN/CCl4-induced and diet-induced hepatocarcinogenesis. [provided by MGI curators]

Dancr

Mus musculus

PHENOTYPE: Homozygous mice for a null allele exhibit reduced hepatocellular carcinoma development and hepatic fibrosis in a DEN-CCl4-induced carcinogenesis model. [provided by MGI curators]

Trem1

Mus musculus

PHENOTYPE: Mice homozygous for a reporter allele exhibit decreased susceptibility to DEN induced tumors and liver damage. Mice homozygous for a knock-out allele of Trem1 and Trem3 exhibit increased susceptibility to P. aeruginosa infection with reduced neutrophil transepithelial migration. [provided by MGI curators]

Clspn

Mus musculus

PHENOTYPE: Homozygous null mice show complete embryonic lethality during organogenesis. Heterozygous null mice exhibit reduced female fertility, develop lymphoid hyperplasia as they age, and show increased susceptibility to non-alcoholic fatty liver disease, and increased liver damage and tumorigenesis in the DEN model of hepatocellular carcinoma. [provided by MGI curators]

Scarf2

Rattus norvegicus

Predicted to enable scavenger receptor activity. Predicted to be involved in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules. Predicted to act upstream of or within vesicle-mediated transport. Human ortholog(s) of this gene implicated in Van den Ende-Gupta syndrome. Orthologous to human SCARF2 (scavenger receptor class F member 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide.