dct-1

Caenorhabditis elegans

Enables protease binding activity and protein homodimerization activity. Involved in several processes, including apoptotic process; determination of adult lifespan; and mitophagy. Located in mitochondrial outer membrane and protein-containing complex. Expressed in body wall musculature; intestine; pharynx; and vulval muscle. Human ortholog(s) of this gene implicated in ductal carcinoma in situ and perinatal necrotizing enterocolitis. Is an ortholog of human BNIP3 (BCL2 interacting protein 3).

tyr-4

Caenorhabditis elegans

Predicted to enable metal ion binding activity and oxidoreductase activity. Human ortholog(s) of this gene implicated in several diseases, including ocular albinism 1; oculocutaneous albinism (multiple); and vitiligo. Is an ortholog of human DCT (dopachrome tautomerase); TYR (tyrosinase); and TYRP1 (tyrosinase related protein 1).

tyr-3

Caenorhabditis elegans

Predicted to enable metal ion binding activity and monooxygenase activity. Expressed in head mesodermal cell. Human ortholog(s) of this gene implicated in several diseases, including ocular albinism 1; oculocutaneous albinism (multiple); and vitiligo. Is an ortholog of human DCT (dopachrome tautomerase) and TYR (tyrosinase).

tyr-1

Caenorhabditis elegans

Predicted to enable metal ion binding activity and monooxygenase activity. Human ortholog(s) of this gene implicated in several diseases, including ocular albinism 1; oculocutaneous albinism (multiple); and vitiligo. Is an ortholog of human DCT (dopachrome tautomerase) and TYR (tyrosinase).

tyr-6

Caenorhabditis elegans

Predicted to enable metal ion binding activity and oxidoreductase activity. Human ortholog(s) of this gene implicated in oculocutaneous albinism type III and pigmentation disease. Is an ortholog of human DCT (dopachrome tautomerase).

spi-1

Caenorhabditis elegans

Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be located in extracellular region.

dcap-1

Caenorhabditis elegans

Predicted to enable mRNA binding activity. Involved in several processes, including determination of adult lifespan; nematode larval development; and response to stress. Located in P granule and P-body. Expressed in head; motor neurons; neurons; tail; and touch receptor neurons. Is an ortholog of human DCP1A (decapping mRNA 1A) and DCP1B (decapping mRNA 1B).

swm-1

Caenorhabditis elegans

Predicted to enable serine-type endopeptidase inhibitor activity. Involved in spermatid development. Located in extracellular space and secretory vesicle. Expressed in body wall musculature; coelomocyte; reproductive tract; and in male.