Enriched in neurons based on RNA-seq studies. Is affected by several genes including prg-1; hrpk-1; and alg-1 based on tiling array and RNA-seq studies. Is affected by nicotine and sanguinarine based on quantitative PCR and RNA-seq studies.
Predicted to enable DNA binding activity. Predicted to be located in nucleus. Expressed in head muscle; intestine; neurons; and somatic nervous system.
Predicted to enable tRNA binding activity. Involved in several processes, including gamete generation; gene expression; and olfactory learning. Located in cytoplasm; neuron projection; and neuronal cell body. Expressed in CAN; HSN; pharynx; sensory neurons; and vulva. Used to study Riley-Day syndrome. Human ortholog(s) of this gene implicated in several diseases, including Riley-Day syndrome; bone structure disease (multiple); and medulloblastoma. Is an ortholog of human ELP1 (elongator acetyltransferase complex subunit 1).
Predicted to enable phosphorylase kinase regulator activity. Involved in several processes, including gamete generation; gene expression; and olfactory learning. Predicted to be located in cytoplasm and nucleus. Predicted to be part of elongator holoenzyme complex. Expressed in CAN; HSN; amphid neurons; pharynx; and vulva. Used to study Riley-Day syndrome. Is an ortholog of human ELP3 (elongator acetyltransferase complex subunit 3).
Predicted to enable alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity. Predicted to contribute to trehalose-phosphatase activity. Predicted to be involved in trehalose biosynthetic process and trehalose metabolism in response to stress. Expressed in hypodermis.
Predicted to enable isocitrate dehydrogenase (NAD+) activity. Involved in protein folding. Located in mitochondrion. Expressed in head and tail. Human ortholog(s) of this gene implicated in retinitis pigmentosa 90. Is an ortholog of human IDH3A (isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha).
Predicted to enable protein phosphatase 2A binding activity and protein phosphatase regulator activity. Involved in embryo development and protein localization to basolateral plasma membrane. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in corpus callosum agenesis-intellectual disability-coloboma-micrognathia syndrome. Is an ortholog of human IGBP1 (immunoglobulin binding protein 1) and IGBP1C (IGBP1 family member C).