Predicted to enable protein tyrosine phosphatase activity. Involved in dauer larval development. Located in plasma membrane. Expressed in XXXL; XXXR; and head. Human ortholog(s) of this gene implicated in artery disease (multiple); proliferative diabetic retinopathy; and type 2 diabetes mellitus. Is an ortholog of human PTPN1 (protein tyrosine phosphatase non-receptor type 1).
Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Involved in cell-cell signaling; dauer larval development; and regulation of cell migration. Located in neuronal cell body and perinuclear region of cytoplasm. Expressed in several structures, including anterior ganglion; excretory cell; intestine; spermatheca; and vulval muscle.
Predicted to enable protein-L-histidine N-pros-methyltransferase activity. Predicted to be involved in methylation. Is an ortholog of human METTL9 (methyltransferase 9, His-X-His N1(pi)-histidine).
Predicted to enable histone methyltransferase activity and metal ion binding activity. Involved in determination of adult lifespan. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in several diseases, including autosomal dominant intellectual developmental disorder 23; esophagus squamous cell carcinoma; and prostate cancer. Is an ortholog of human SETD5 (SET domain containing 5).
Predicted to enable hormone activity. Predicted to be involved in signal transduction. Predicted to be located in extracellular region. Expressed in coelomocyte; intestine; nerve ring; and neurons.
Predicted to be located in mitochondrion. Is an ortholog of several human genes including ARMCX1 (armadillo repeat containing X-linked 1); ARMCX2 (armadillo repeat containing X-linked 2); and ARMCX3 (armadillo repeat containing X-linked 3).