cye-1

Caenorhabditis elegans

Enables cyclin-dependent protein serine/threonine kinase regulator activity. Involved in several processes, including developmental process involved in reproduction; regulation of mitotic cell cycle; and regulation of protein localization. Located in nucleus. Part of chromatin. Expressed in several structures, including germ line; gonad; and male sex myoblast. Human ortholog(s) of this gene implicated in carcinoma (multiple); cervix uteri carcinoma in situ; and urinary bladder cancer. Is an ortholog of human CCNE1 (cyclin E1) and CCNE2 (cyclin E2).

C50B6.1

Caenorhabditis elegans

Enriched in muscle cell based on microarray studies. Is affected by several genes including cyd-1; cye-1; and rsr-2 based on tiling array; microarray; and RNA-seq studies. Is affected by dibromoacetic acid and adsorbable organic bromine compound based on microarray studies.

cdk-2

Caenorhabditis elegans

Predicted to enable cyclin binding activity and cyclin-dependent protein serine/threonine kinase activity. Involved in several processes, including pseudocleavage; regulation of mitotic cell cycle; and regulation of protein localization. Part of chromatin.

B0334.10

Caenorhabditis elegans

Enriched in germ line; neurons; and in male based on RNA-seq studies. Is affected by several genes including cyc-1; cye-1; and atx-3 based on microarray and RNA-seq studies. Is affected by six chemicals including methylmercuric chloride; Doxycycline; and Chlorpyrifos based on microarray and RNA-seq studies.

nspc-12

Caenorhabditis elegans

Enriched in excretory gland cell based on single-cell RNA-seq studies. Is affected by several genes including cyd-1; cye-1; and etr-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including hydrogen sulfide; mianserin; and metformin based on microarray and RNA-seq studies.

F48C1.9

Caenorhabditis elegans

Enriched in hyp12 and hypodermis based on tiling array and single-cell RNA-seq studies. Is affected by several genes including cyc-1; cye-1; and mxl-2 based on microarray and RNA-seq studies. Is affected by twenty-five chemicals including 1-methylnicotinamide; methylmercuric chloride; and rotenone based on RNA-seq and microarray studies.

F32D8.11

Caenorhabditis elegans

Enriched in intestine; neurons; and retrovesicular ganglion based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including cye-1; nuo-6; and atfs-1 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including D-glucopyranose; stavudine; and Zidovudine based on RNA-seq and microarray studies.

lips-16

Caenorhabditis elegans

Enriched in excretory cell; hermaphrodite gonad; and neurons based on tiling array; single-cell RNA-seq; and microarray studies. Is affected by several genes including cyd-1; cye-1; and nuo-6 based on tiling array; microarray; and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; rotenone; and stavudine based on microarray and RNA-seq studies.

nspc-10

Caenorhabditis elegans

Enriched in excretory gland cell; intestine; and neurons based on single-cell RNA-seq and microarray studies. Is affected by several genes including hyl-2; cye-1; and nuo-6 based on RNA-seq and microarray studies. Is affected by twenty-two chemicals including hydrogen sulfide; D-glucose; and bisphenol A based on microarray and RNA-seq studies.

Y82E9BR.6

Caenorhabditis elegans

Enriched in GABAergic neurons; body wall musculature; and pharyngeal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including cyd-1; cye-1; and mter-4 based on microarray and RNA-seq studies. Is affected by seven chemicals including metformin; Psoralens; and allantoin based on RNA-seq and microarray studies.