cps-6

Caenorhabditis elegans

Enables endonuclease activity; protein homodimerization activity; and sequence-specific DNA binding activity. Involved in RNA catabolic process and apoptotic DNA fragmentation. Located in mitochondrial intermembrane space. Is an ortholog of human ENDOG (endonuclease G).

mau-8

Caenorhabditis elegans

Expressed in body wall musculature; germ line; hypodermis; intestine; and pharynx. Is an ortholog of human PDC (phosducin) and PDCL (phosducin like).

Y48B6A.17

Caenorhabditis elegans

Is affected by several genes including puf-8; npr-8; and ins-11 based on RNA-seq studies. Is affected by paraquat based on RNA-seq studies.

set-8

Caenorhabditis elegans

Predicted to enable double-stranded DNA binding activity and histone methyltransferase activity. Predicted to be involved in chromatin remodeling. Predicted to be located in nucleus.

Y49F6B.20

Caenorhabditis elegans

Is affected by nhr-8 based on RNA-seq studies.

F19B6.9

Caenorhabditis elegans

Is affected by npr-8 based on RNA-seq studies.

wah-1

Caenorhabditis elegans

Enables enzyme binding activity. Involved in apoptotic DNA fragmentation and positive regulation of phosphatidylserine exposure on apoptotic cell surface. Located in cytosol; mitochondrion; and nucleus. Human ortholog(s) of this gene implicated in Alzheimer's disease; X-linked recessive disease (multiple); and dilated cardiomyopathy 1H. Is an ortholog of human AIFM1 (apoptosis inducing factor mitochondria associated 1).

flp-8

Caenorhabditis elegans

Involved in negative regulation of turning behavior involved in mating. Predicted to be located in extracellular region. Expressed in PVM; head; nerve ring; and tail.

sma-8

Caenorhabditis elegans

him-8

Caenorhabditis elegans

Involved in meiotic chromosome segregation. Located in X chromosome; condensed nuclear chromosome; and nuclear envelope.