coq-4

Caenorhabditis elegans

Involved in ubiquinone biosynthetic process. Predicted to be located in mitochondrion. Predicted to be extrinsic component of mitochondrial inner membrane. Human ortholog(s) of this gene implicated in primary coenzyme Q10 deficiency 7 and spastic ataxia. Is an ortholog of human COQ4 (coenzyme Q4).

coq-3

Caenorhabditis elegans

Predicted to enable 3,4-dihydroxy-5-polyprenylbenzoic acid O-methyltransferase activity. Involved in nematode larval development and ubiquinone biosynthetic process. Predicted to be located in mitochondrial inner membrane. Predicted to be extrinsic component of mitochondrial inner membrane. Is an ortholog of human COQ3 (coenzyme Q3, methyltransferase).

coq-2

Caenorhabditis elegans

Predicted to enable 4-hydroxybenzoate decaprenyltransferase activity. Involved in ubiquinone biosynthetic process. Predicted to be located in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in primary coenzyme Q10 deficiency 1. Is an ortholog of human COQ2 (coenzyme Q2, polyprenyltransferase).

coq-1

Caenorhabditis elegans

Predicted to enable prenyltransferase activity. Involved in ubiquinone biosynthetic process. Predicted to be extrinsic component of mitochondrial inner membrane. Predicted to be part of transferase complex. Human ortholog(s) of this gene implicated in primary coenzyme Q10 deficiency 2. Is an ortholog of human PDSS1 (decaprenyl diphosphate synthase subunit 1).

coq-8

Caenorhabditis elegans

Predicted to enable ATP binding activity and transferase activity. Involved in ubiquinone biosynthetic process. Predicted to be located in mitochondrion. Expressed in coelomocyte; hypodermis; muscle cell; and neurons. Human ortholog(s) of this gene implicated in nephrotic syndrome type 9 and primary coenzyme Q10 deficiency 4. Is an ortholog of human COQ8A (coenzyme Q8A) and COQ8B (coenzyme Q8B).

coq-5

Caenorhabditis elegans

Predicted to enable 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity. Involved in ubiquinone biosynthetic process. Predicted to be located in mitochondrial inner membrane. Predicted to be extrinsic component of mitochondrial inner membrane. Human ortholog(s) of this gene implicated in primary coenzyme Q10 deficiency 9. Is an ortholog of human COQ5 (coenzyme Q5, methyltransferase).

coq-6

Caenorhabditis elegans

Predicted to enable oxidoreductase activity. Involved in ubiquinone biosynthetic process. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in primary coenzyme Q10 deficiency 6. Is an ortholog of human COQ6 (coenzyme Q6, monooxygenase).

T22D1.5

Caenorhabditis elegans

Predicted to enable protein phosphatase regulator activity. Predicted to be part of protein phosphatase type 2A complex.

D2023.6

Caenorhabditis elegans

Predicted to enable kinase activity. Predicted to be involved in lipid homeostasis and mitochondrion organization. Predicted to be located in mitochondrial inner membrane. Is an ortholog of human ADCK1 (aarF domain containing kinase 1).

T20D3.6

Caenorhabditis elegans

Predicted to be involved in mitochondrial respirasome assembly. Located in cytoplasm. Is an ortholog of human HIGD2A (HIG1 hypoxia inducible domain family member 2A).