cki-1

Caenorhabditis elegans

Predicted to enable cyclin-dependent protein serine/threonine kinase inhibitor activity. Involved in several processes, including gonad development; regulation of cell cycle process; and regulation of cell division. Located in nucleus. Expressed in several structures, including excretory duct; hermaphrodite somatic gonadal cell; hypodermal cell; pharynx; and somatic gonad precursor. Human ortholog(s) of this gene implicated in several diseases, including hematologic cancer (multiple); lung carcinoma (multiple); and urinary system cancer (multiple). Is an ortholog of human CDKN1B (cyclin dependent kinase inhibitor 1B).

cki-2

Caenorhabditis elegans

Predicted to enable cyclin-dependent protein serine/threonine kinase inhibitor activity. Involved in gonad development; regulation of cell cycle process; and regulation of cell division. Predicted to be located in nucleus. Expressed in several structures, including P3.pa; P3.pp; P5.ppp; P7.paa; and germ line. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); hematologic cancer (multiple); and urinary system cancer (multiple). Is an ortholog of human CDKN1B (cyclin dependent kinase inhibitor 1B).

pho-1

Caenorhabditis elegans

Predicted to enable phosphatase activity. Located in membrane raft. Expressed in intestine. Used to study obesity.

C35D10.17

Caenorhabditis elegans

Predicted to be located in mitochondrion. Is an ortholog of human CMC2 (C-X9-C motif containing 2).

scbp-2

Caenorhabditis elegans

Predicted to be located in ribosome.

clec-191

Caenorhabditis elegans

Is affected by hpl-2 and rsr-2 based on tiling array studies. Is affected by four chemicals including Progesterone; Atrazine; and fluoranthene based on microarray studies. Is predicted to encode a protein with the following domains: PAN-3 domain; PAN-like domain; C-type lectin-like/link domain superfamily; C-type lectin-like; and C-type lectin fold.

fab-2

Caenorhabditis elegans

clec-128

Caenorhabditis elegans

Enriched in NSM based on tiling array studies. Is affected by daf-2; daf-18; and eat-2 based on RNA-seq and microarray studies. Is affected by resveratrol; fluoranthene; and adsorbable organic bromine compound based on microarray studies. Is predicted to encode a protein with the following domains: Phosphorylation site; C-type lectin-like/link domain superfamily; Lectin C-type domain; C-type lectin-like; and C-type lectin fold.

fce-2

Caenorhabditis elegans

Enables cysteine-type endopeptidase activity. Involved in CAAX-box protein processing. Located in membrane. Is an ortholog of human RCE1 (Ras converting CAAX endopeptidase 1).

liv-2

Caenorhabditis elegans