let-418

Caenorhabditis elegans

Enables RNA polymerase II-specific DNA-binding transcription factor binding activity. Contributes to RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in embryonic digestive tract morphogenesis; negative regulation of transcription by RNA polymerase II; and negative regulation of vulval development. Part of RNA polymerase II transcription repressor complex. Expressed in several structures, including P3.p hermaphrodite; P4.p hermaphrodite; P8.p hermaphrodite; gonad; and somatic nervous system. Human ortholog(s) of this gene implicated in several diseases, including Sifrim-Hitz-Weiss syndrome; gastrointestinal system cancer (multiple); and lung adenocarcinoma. Is an ortholog of human CHD3 (chromodomain helicase DNA binding protein 3).

K03H9.6

Caenorhabditis elegans

Is affected by several genes including glh-4; glh-1; and chd-3 based on RNA-seq studies.

21ur-3689

Caenorhabditis elegans

Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including glh-4; glh-1; and chd-3 based on RNA-seq studies.

ZK380.3

Caenorhabditis elegans

Enriched in anchor cell based on RNA-seq studies. Is affected by several genes including glh-4; glh-1; and chd-3 based on RNA-seq studies.

T05B11.10

Caenorhabditis elegans

Is affected by chd-3 based on RNA-seq studies.

21ur-7464

Caenorhabditis elegans

Is affected by chd-3 based on RNA-seq studies.

T07D1.9

Caenorhabditis elegans

Is affected by chd-3 based on RNA-seq studies.

21ur-6661

Caenorhabditis elegans

Is affected by chd-3 based on RNA-seq studies.

F54D5.20

Caenorhabditis elegans

Is affected by chd-3 based on RNA-seq studies.

21ur-14951

Caenorhabditis elegans

Is affected by chd-3 and wdr-5.1 based on RNA-seq studies.