Enables cGMP-dependent protein kinase activity. Involved in several processes, including enzyme-linked receptor protein signaling pathway; regulation of multicellular organismal process; and regulation of signal transduction. Located in cytosol and nucleus. Expressed in several structures, including marginal cell; nerve ring; neurons; spermatheca; and vulval muscle. Used to study ciliopathy. Human ortholog(s) of this gene implicated in thoracic aortic aneurysm. Is an ortholog of human PRKG1 (protein kinase cGMP-dependent 1).