Enables Wnt-protein binding activity; frizzled binding activity; and transmembrane receptor protein tyrosine kinase activity. Involved in generation of neurons and neuroblast migration. Located in axon; neuromuscular junction; and somatodendritic compartment. Expressed in several structures, including QL.aa; head; neurons; pharynx; and seam cell. Human ortholog(s) of this gene implicated in several diseases, including autosomal recessive Robinow syndrome; autosomal recessive nonsyndromic deafness 108; and brachydactyly type B1. Is an ortholog of human ROR1 (receptor tyrosine kinase like orphan receptor 1).
Enables calmodulin binding activity and calmodulin-dependent protein kinase activity. Predicted to be involved in CAMKK-AMPK signaling cascade. Located in cytoplasm and nucleus. Expressed in head neurons; tail neurons; and vulval muscle. Human ortholog(s) of this gene implicated in high grade glioma. Is an ortholog of human CAMKK1 (calcium/calmodulin dependent protein kinase kinase 1).
Predicted to enable potassium:proton antiporter activity and sodium:proton antiporter activity. Involved in several processes, including defecation; lipid transport involved in lipid storage; and positive regulation of multicellular organismal process. Located in basolateral plasma membrane. Expressed in intestine.