Predicted to enable dynein intermediate chain binding activity; dynein light intermediate chain binding activity; and minus-end-directed microtubule motor activity. Involved in several processes, including dauer entry; non-motile cilium assembly; and positive regulation of dauer larval development. Located in non-motile cilium. Expressed in I4 neuron; PDEL; PDER; and nerve ring. Human ortholog(s) of this gene implicated in asphyxiating thoracic dystrophy 3. Is an ortholog of human DYNC2H1 (dynein cytoplasmic 2 heavy chain 1).
Predicted to be involved in nucleosome assembly. Predicted to be located in nucleus. Predicted to be part of CAF-1 complex. Human ortholog(s) of this gene implicated in several diseases, including colon cancer; neuroblastoma; and systemic lupus erythematosus. Is an ortholog of human CHAF1A (chromatin assembly factor 1 subunit A).
Predicted to be involved in nucleosome assembly. Predicted to be located in nucleus. Predicted to be part of CAF-1 complex. Human ortholog(s) of this gene implicated in several diseases, including glioblastoma; oral squamous cell carcinoma; and skin melanoma. Is an ortholog of human CHAF1B (chromatin assembly factor 1 subunit B).