Y67A10A.7

Caenorhabditis elegans

Predicted to be located in mitochondrion. Is an ortholog of several human genes including ARMCX1 (armadillo repeat containing X-linked 1); ARMCX2 (armadillo repeat containing X-linked 2); and ARMCX3 (armadillo repeat containing X-linked 3).

dpy-27

Caenorhabditis elegans

Enables sequence-specific DNA binding activity. Involved in dosage compensation by hypoactivation of X chromosome. Located in X chromosome and nuclear chromosome. Part of dosage compensation complex. Is an ortholog of human SMC4 (structural maintenance of chromosomes 4).

him-7

Caenorhabditis elegans

sdc-2

Caenorhabditis elegans

Involved in dosage compensation by hypoactivation of X chromosome and negative regulation of transcription by RNA polymerase II. Located in nuclear chromosome.

rec-1

Caenorhabditis elegans

Involved in meiotic DNA double-strand break formation involved in reciprocal meiotic recombination.

him-2

Caenorhabditis elegans

sex-2

Caenorhabditis elegans

Acts upstream of or within primary sex determination and transcription by RNA polymerase II.

dpy-26

Caenorhabditis elegans

Involved in dosage compensation by hypoactivation of X chromosome; meiotic sister chromatid segregation; and mitotic sister chromatid segregation. Located in condensed nuclear chromosome. Part of dosage compensation complex. Expressed widely.

F38E9.1

Caenorhabditis elegans

Predicted to enable phosphoric diester hydrolase activity. Predicted to be involved in lipid metabolic process. Is an ortholog of human PLCXD2 (phosphatidylinositol specific phospholipase C X domain containing 2) and PLCXD3 (phosphatidylinositol specific phospholipase C X domain containing 3).

mix-1

Caenorhabditis elegans

Predicted to enable chromatin binding activity. Involved in several processes, including dosage compensation by hypoactivation of X chromosome; mitotic chromosome condensation; and positive regulation of nematode male tail tip morphogenesis. Located in chromosome, centromeric region and condensed chromosome. Part of dosage compensation complex. Expressed in AB. Human ortholog(s) of this gene implicated in colon adenocarcinoma. Is an ortholog of human SMC2 (structural maintenance of chromosomes 2).