Bma-vps-37

Brugia malayi

Enriched in reproductive tract based on proteomic studies. Is affected by ivermectin based on RNA-seq studies. Is predicted to encode a protein with the following domains: Helix hairpin bin domain superfamily; Modifier of rudimentary, Modr; Modifier of rudimentary (Mod(r)) protein; and ESCRT assembly domain. Is an ortholog of C. elegans vps-37. In C. elegans, vps-37 is involved in receptor catabolic process.

Bm10299

Brugia malayi

Is predicted to encode a protein with the following domains: 14-3-3 protein; 14-3-3 domain superfamily; and 14-3-3 domain.

Bma-ftt-2.1

Brugia malayi

Is predicted to encode a protein with the following domains: 14-3-3 protein; 14-3-3 domain superfamily; and 14-3-3 domain. Is an ortholog of C. elegans M117.3; ftt-2; and par-5. In C. elegans, ftt-2 is involved in cytoplasmic sequestering of protein; dauer larval development; and negative regulation of protein import into nucleus.

Bma-ftt-2.2

Brugia malayi

Is predicted to encode a protein with the following domains: 14-3-3 protein; 14-3-3 domain superfamily; and 14-3-3 domain. Is an ortholog of C. elegans M117.3; ftt-2; and par-5. In C. elegans, ftt-2 is involved in cytoplasmic sequestering of protein; dauer larval development; and negative regulation of protein import into nucleus.

Bma-ints-3

Brugia malayi

Is affected by 20-hydroxyecdysone based on proteomic studies. Is predicted to encode a protein with the following domains: Integrator complex subunit 3 N-terminal; Integrator complex subunit 3, N-terminal; and Integrator complex subunit 3. Is an ortholog of C. elegans ints-3.

Bma-gpdh-3

Brugia malayi

Predicted to enable calcium ion binding activity and glycerol-3-phosphate dehydrogenase (quinone) activity. Predicted to be involved in glycerol-3-phosphate metabolic process. Is an ortholog of C. elegans gpdh-3.

Bm5782

Brugia malayi

Is predicted to encode a protein with the following domains: Resistance to inhibitors of cholinesterase protein 3; Resistance to inhibitors of cholinesterase homologue 3; and Resistance to inhibitors of cholinesterase protein 3, N-terminal.

Bm4700

Brugia malayi

Is predicted to encode a protein with the following domains: Optic atrophy 3 protein (OPA3) and Optic atrophy 3-like.

Bma-arx-3

Brugia malayi

Predicted to be involved in Arp2/3 complex-mediated actin nucleation. Predicted to be located in actin cytoskeleton. Predicted to be part of Arp2/3 protein complex. Is an ortholog of C. elegans arx-3.

Bma-coq-3

Brugia malayi

Predicted to enable 3,4-dihydroxy-5-polyprenylbenzoic acid O-methyltransferase activity and 3-demethylubiquinol-n 3-O-methyltransferase activity. Predicted to be involved in ubiquinone biosynthetic process. Is an ortholog of C. elegans coq-3. In C. elegans, coq-3 is involved in nematode larval development and ubiquinone biosynthetic process.