dhs-11

Caenorhabditis elegans

Predicted to enable oxidoreductase activity. Is an ortholog of human HSD17B8 (hydroxysteroid 17-beta dehydrogenase 8).

mau-8

Caenorhabditis elegans

Expressed in body wall musculature; germ line; hypodermis; intestine; and pharynx. Is an ortholog of human PDC (phosducin) and PDCL (phosducin like).

dhs-25

Caenorhabditis elegans

Predicted to enable oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. Is an ortholog of human HSD17B8 (hydroxysteroid 17-beta dehydrogenase 8).

egl-8

Caenorhabditis elegans

Predicted to enable phosphatidylinositol phospholipase C activity. Involved in several processes, including G protein-coupled dopamine receptor signaling pathway; positive regulation of acetylcholine secretion, neurotransmission; and taxis. Located in plasma membrane. Expressed in intestine; nervous system; non-striated muscle; and vas deferens. Used to study nicotine dependence. Is an ortholog of human PLCB4 (phospholipase C beta 4).

nas-8

Caenorhabditis elegans

Predicted to enable metalloendopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in extracellular region. Is an ortholog of human ASTL (astacin like metalloendopeptidase); MEP1A (meprin A subunit alpha); and MEP1B (meprin A subunit beta).

lact-8

Caenorhabditis elegans

Enriched in several structures, including ABarpaapap; AFD; excretory pore; ganglia; and hypodermis based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including swsn-2.2; atfs-1; and etr-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including levamisole; allantoin; and Sirolimus based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Beta-lactamase/transpeptidase-like; Bacterial Cell Wall Synthesis and Modification; Beta-lactamase; and Beta-lactamase-related.

Y48B6A.17

Caenorhabditis elegans

Is affected by several genes including puf-8; npr-8; and ins-11 based on RNA-seq studies. Is affected by paraquat based on RNA-seq studies.

set-8

Caenorhabditis elegans

Predicted to enable double-stranded DNA binding activity and histone methyltransferase activity. Predicted to be involved in chromatin remodeling. Predicted to be located in nucleus.

Y49F6B.20

Caenorhabditis elegans

Is affected by nhr-8 based on RNA-seq studies.

F19B6.9

Caenorhabditis elegans

Is affected by npr-8 based on RNA-seq studies.