pbs-5

Caenorhabditis elegans

Predicted to enable endopeptidase activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in cytosol and nucleus. Predicted to be part of proteasome core complex, beta-subunit complex. Human ortholog(s) of this gene implicated in proteasome-associated autoinflammatory syndrome 1. Is an ortholog of human PSMB5 (proteasome 20S subunit beta 5).

bre-5

Caenorhabditis elegans

Enables acetylglucosaminyltransferase activity. Involved in several processes, including carbohydrate biosynthetic process; positive regulation of Notch signaling pathway; and regulation of mesodermal cell fate specification. Predicted to be located in Golgi membrane. Human ortholog(s) of this gene implicated in pancreatic cancer. Is an ortholog of human B3GALNT1 (beta-1,3-N-acetylgalactosaminyltransferase 1 (Globoside blood group)); B3GALT9 (beta-1,3-galactosyltransferase 9); and B3GNT5 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5).

F48F7.3

Caenorhabditis elegans

Predicted to enable glycosyltransferase activity. Predicted to be involved in protein O-linked glycosylation. Predicted to be located in Golgi membrane. Is an ortholog of human B3GALT4 (beta-1,3-galactosyltransferase 4) and B3GNT5 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5).

hex-5

Caenorhabditis elegans

Enables hexosaminidase activity. Involved in carbohydrate metabolic process. Expressed in head muscle; tail; and vulva. Is an ortholog of human HEXD (hexosaminidase D).

lact-5

Caenorhabditis elegans

Enriched in several structures, including VB2; anterior hypodermis; rectal epithelium; sensory neurons; and somatic neurons based on tiling array; RNA-seq; proteomic; and single-cell RNA-seq studies. Is affected by several genes including nuo-6; numr-2; and numr-1 based on microarray and RNA-seq studies. Is affected by twenty chemicals including 1-methylnicotinamide; 4-bromodiphenyl ether; and D-glucose based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Beta-lactamase/esterase domain-containing protein; Beta-lactamase/transpeptidase-like; Beta-lactamase; and Beta-lactamase-related.

pbs-2

Caenorhabditis elegans

Predicted to enable endopeptidase activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in cytosol and nucleus. Predicted to be part of proteasome core complex, beta-subunit complex. Human ortholog(s) of this gene implicated in proteosome-associated autoinflammatory syndrome 5. Is an ortholog of human PSMB7 (proteasome 20S subunit beta 7).

B0024.15

Caenorhabditis elegans

Predicted to enable glycosyltransferase activity. Predicted to be involved in protein O-linked glycosylation. Predicted to be located in Golgi membrane. Human ortholog(s) of this gene implicated in pancreatic cancer. Is an ortholog of human B3GALT5 (beta-1,3-galactosyltransferase 5).

copb-1

Caenorhabditis elegans

Predicted to enable structural molecule activity. Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport and intra-Golgi vesicle-mediated transport. Predicted to be located in COPI-coated vesicle membrane and Golgi membrane. Predicted to be part of COPI vesicle coat. Expressed in head and tail. Is an ortholog of human COPB1 (COPI coat complex subunit beta 1).

bre-3

Caenorhabditis elegans

Predicted to enable beta-1,4-mannosyltransferase activity. Involved in carbohydrate biosynthetic process and response to toxic substance. Located in cytoplasm. Expressed in head neurons.

C33G3.4

Caenorhabditis elegans

Predicted to enable beta-mannosidase activity. Predicted to be involved in glycoprotein catabolic process. Predicted to be located in lysosome. Human ortholog(s) of this gene implicated in beta-mannosidosis. Is an ortholog of human MANBA (mannosidase beta).