Enriched in AVM; PHCL; PVM; and RIPL based on single-cell RNA-seq studies. Is affected by several genes including spr-5; unc-30; and ilc-17.1 based on RNA-seq studies.
Predicted to enable hydroxymethylglutaryl-CoA lyase activity. Predicted to be involved in L-leucine catabolic process and ketone body biosynthetic process. Human ortholog(s) of this gene implicated in amino acid metabolic disorder. Is an ortholog of human HMGCL (3-hydroxy-3-methylglutaryl-CoA lyase) and HMGCLL1 (3-hydroxy-3-methylglutaryl-CoA lyase like 1).