atf-2

Caenorhabditis elegans

Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity and protein heterodimerization activity. Involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in digestive tract; egg-laying apparatus; excretory system; neurons; and ventral nerve cord. Human ortholog(s) of this gene implicated in severe acute respiratory syndrome. Is an ortholog of human NFIL3 (nuclear factor, interleukin 3 regulated) and NFILZ (NFIL3 like basic leucine zipper).

H02F09.2

Caenorhabditis elegans

Is affected by several genes including atf-7; etr-1; and rsr-2 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including Cadmium Chloride; Ag nanoparticles; and Cry5B based on RNA-seq and microarray studies.

atf-6

Caenorhabditis elegans

Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including ATF6-mediated unfolded protein response; determination of adult lifespan; and endoplasmic reticulum calcium ion homeostasis. Predicted to be located in nucleus. Expressed in several structures, including intestine; muscle cell; pharyngeal gland cell; rectum; and vulva. Human ortholog(s) of this gene implicated in achromatopsia 7. Is an ortholog of human ATF6 (activating transcription factor 6) and ATF6B (activating transcription factor 6 beta).

Y71A12B.14

Caenorhabditis elegans

Enriched in AVK and head mesodermal cell based on RNA-seq studies. Is affected by several genes including nuo-6; atf-6; and etr-1 based on RNA-seq and microarray studies.

F55G11.6

Caenorhabditis elegans

Is affected by several genes including atf-7; rsr-2; and fshr-1 based on microarray; RNA-seq; tiling array; and proteomic studies. Is affected by ten chemicals including Mercuric Chloride; Tunicamycin; and sodium arsenite based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: CUB-like domain.

F17B5.8

Caenorhabditis elegans

Enriched in OLL; PVD; and intestine based on tiling array and RNA-seq studies. Is affected by several genes including numr-2; numr-1; and atf-7 based on proteomic; tiling array; RNA-seq; and microarray studies. Is affected by eighteen chemicals including tryptophan; Tunicamycin; and sodium arsenite based on microarray and RNA-seq studies.

Y47D3B.12

Caenorhabditis elegans

Enriched in AS neuron; coelomocyte; excretory gland cell; and uterine seam cell based on single-cell RNA-seq studies. Is affected by several genes including numr-2; numr-1; and atf-7 based on RNA-seq and microarray studies. Is affected by nine chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies.

F55G11.3

Caenorhabditis elegans

Is affected by several genes including cyc-1; atf-7; and etr-1 based on microarray and RNA-seq studies. Is affected by six chemicals including allantoin; Sirolimus; and Psoralens based on RNA-seq studies.

T19D12.3

Caenorhabditis elegans

Enriched in CEP socket cell; GABAergic neurons; excretory cell; and intestine based on tiling array; single-cell RNA-seq; and microarray studies. Is affected by several genes including atf-7; etr-1; and rsr-2 based on microarray; RNA-seq; and tiling array studies. Is affected by seventeen chemicals including methylmercuric chloride; Mercuric Chloride; and Tunicamycin based on microarray and RNA-seq studies.

H12I13.6

Caenorhabditis elegans

Enriched in excretory cell; germ line; interfacial epithelial cell; and in male based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including atf-7; ash-2; and drh-3 based on microarray and RNA-seq studies. Is affected by five chemicals including Ethanol; rifampin; and allantoin based on RNA-seq and microarray studies.