Bma-arf-1

Brugia malayi

Predicted to enable GTP binding activity and GTPase activity. Is an ortholog of C. elegans arf-1. In C. elegans, arf-1 is involved in several processes, including oocyte development; regulation of apoptotic process involved in development; and regulation of receptor-mediated endocytosis.

Bma-arf-5

Brugia malayi

Predicted to enable GTP binding activity and GTPase activity. Is an ortholog of C. elegans arf-5. In C. elegans, arf-5 is involved in embryo development and germ cell development.

Bm10041

Brugia malayi

Is an ortholog of C. elegans mdt-1.2 and sop-3.

Bma-got-1.2

Brugia malayi

Predicted to enable pyridoxal phosphate binding activity and transaminase activity. Predicted to be involved in amino acid metabolic process and biosynthetic process. Is an ortholog of C. elegans got-1.2. In C. elegans, got-1.2 is involved in positive regulation of glutamate metabolic process.

Bm4602

Brugia malayi

Predicted to be located in endoplasmic reticulum. Is an ortholog of C. elegans serp-1.1 and serp-1.2.

Bma-ltah-1.2

Brugia malayi

Predicted to enable metallopeptidase activity and zinc ion binding activity. Predicted to be involved in proteolysis. Is an ortholog of C. elegans ltah-1.2. In C. elegans, ltah-1.2 is involved in negative regulation of fatty acid transport; regulation of lipid storage; and regulation of peptide transport.

Bma-agef-1

Brugia malayi

Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in regulation of ARF protein signal transduction. Is an ortholog of C. elegans agef-1.

Bm4843

Brugia malayi

Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in regulation of ARF protein signal transduction. Is an ortholog of O. volvulus Ovo-grp-1.

Bm5066

Brugia malayi

Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in regulation of ARF protein signal transduction. Is an ortholog of C. elegans bris-1 and mon-2.

Bma-hmg-1.2

Brugia malayi

Is affected by ivermectin based on RNA-seq studies. Is predicted to encode a protein with the following domains: High mobility group box domain; High mobility group box domain superfamily; HMG-box domain; and HMG (high mobility group) box. Is an ortholog of C. elegans hmg-1.2. In C. elegans, hmg-1.2 is involved in several processes, including gonad development; positive regulation of transcription by RNA polymerase II; and vulval development.