ani-1

Caenorhabditis elegans

Enables actin filament binding activity; microtubule binding activity; and small GTPase binding activity. Involved in several processes, including cytoskeleton organization; first cell cycle pseudocleavage; and nematode male tail tip morphogenesis. Located in several cellular components, including cleavage furrow; growth cone; and midbody. Expressed in several structures, including QL.a; QL.pa; germ line; neuroblasts; and neurons. Human ortholog(s) of this gene implicated in focal segmental glomerulosclerosis 8. Is an ortholog of human ANLN (anillin, actin binding protein).

mig-2

Caenorhabditis elegans

Enables GTPase activity and protein kinase binding activity. Involved in several processes, including actin cytoskeleton organization; axon guidance; and cell migration. Located in cytoplasm; cytoplasmic side of plasma membrane; and neuron projection. Expressed in several structures, including CAN; HSN; distal tip cell; touch receptor neurons; and vulval cell. Used to study epilepsy. Is an ortholog of human RHOG (ras homolog family member G).

zip-1

Caenorhabditis elegans

Predicted to enable DNA binding activity.

yrn-1

Caenorhabditis elegans

Part of ribonucleoprotein complex.

amt-1

Caenorhabditis elegans

Predicted to enable ammonium channel activity. Predicted to be involved in ammonium homeostasis and ammonium transmembrane transport. Predicted to be located in plasma membrane.

cal-4

Caenorhabditis elegans

Predicted to enable calcium ion binding activity. Predicted to be located in cytoplasm.

cal-1

Caenorhabditis elegans

Predicted to enable calcium ion binding activity. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in Alzheimer's disease. Is an ortholog of human CALML3 (calmodulin like 3); CALML4 (calmodulin like 4); and CALML5 (calmodulin like 5).

gly-1

Caenorhabditis elegans

Predicted to enable glycosyltransferase activity. Predicted to be located in Golgi membrane. Expressed in pharyngeal neurons and seam cell. Is an ortholog of several human genes including GCNT1 (glucosaminyl (N-acetyl) transferase 1); GCNT3 (glucosaminyl (N-acetyl) transferase 3, mucin type); and GCNT4 (glucosaminyl (N-acetyl) transferase 4).

gna-1

Caenorhabditis elegans

Predicted to enable glucosamine 6-phosphate N-acetyltransferase activity. Predicted to be involved in UDP-N-acetylglucosamine biosynthetic process. Is an ortholog of human GNPNAT1 (glucosamine-phosphate N-acetyltransferase 1).

jtr-1

Caenorhabditis elegans

Predicted to be involved in mitotic cytokinesis. Predicted to be located in cytoplasm; microtubule cytoskeleton; and midbody. Is an ortholog of human JTB (jumping translocation breakpoint).