algn-8

Caenorhabditis elegans

Predicted to enable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity. Predicted to be involved in dolichol-linked oligosaccharide biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ih and polycystic liver disease. Is an ortholog of human ALG8 (ALG8 alpha-1,3-glucosyltransferase).

aqp-8

Caenorhabditis elegans

Predicted to enable glycerol channel activity and water channel activity. Predicted to be involved in glycerol transmembrane transport and water transport. Located in cell surface. Expressed in several structures, including excretory system; germ line; intestinal cell; non-striated muscle; and ray. Human ortholog(s) of this gene implicated in several diseases, including brain edema; inflammatory bowel disease (multiple); and morbid obesity. Is an ortholog of several human genes including AQP3 (aquaporin 3 (Gill blood group)); AQP7 (aquaporin 7); and AQP9 (aquaporin 9).

arrd-8

Caenorhabditis elegans

Predicted to be involved in protein transport. Predicted to be located in cytoplasm. Is an ortholog of human ARRDC2 (arrestin domain containing 2).

asp-8

Caenorhabditis elegans

Predicted to enable aspartic-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in lysosome. Is an ortholog of human PGC (progastricsin).

bbs-8

Caenorhabditis elegans

Involved in several processes, including cilium organization; olfactory learning; and regulation of cellular localization. Located in cilium and dendrite terminus. Expressed in ciliated neurons; head; and sensory neurons. Used to study Bardet-Biedl syndrome and ciliopathy. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome 8 and retinitis pigmentosa 51. Is an ortholog of human TTC8 (tetratricopeptide repeat domain 8).

cdh-8

Caenorhabditis elegans

Predicted to enable calcium ion binding activity. Predicted to be involved in cell-cell adhesion. Predicted to be located in membrane.

cdk-8

Caenorhabditis elegans

Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in G1/S transition of mitotic cell cycle. Predicted to be located in nucleus. Expressed in anchor cell and neurons. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 87 and dilated cardiomyopathy. Is an ortholog of human CDK19 (cyclin dependent kinase 19) and CDK8 (cyclin dependent kinase 8).

clc-8

Caenorhabditis elegans

Predicted to be located in membrane.

clp-8

Caenorhabditis elegans

Predicted to enable calcium-dependent cysteine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in cytoplasm.

cod-8

Caenorhabditis elegans