Bma-acr-8

Brugia malayi

Predicted to enable acetylcholine-gated monoatomic cation-selective channel activity and transmembrane signaling receptor activity. Predicted to be involved in monoatomic ion transmembrane transport. Predicted to be located in postsynaptic membrane. Is an ortholog of C. elegans acr-8.

Bma-ceh-8

Brugia malayi

Predicted to enable DNA binding activity. Is an ortholog of C. elegans ceh-8. In C. elegans, ceh-8 is involved in neuron differentiation.

Bma-coq-8

Brugia malayi

Is affected by 20-hydroxyecdysone and ivermectin based on proteomic and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein kinase-like domain superfamily and ABC1 atypical kinase-like domain. Is an ortholog of C. elegans coq-8. In C. elegans, coq-8 is involved in ubiquinone biosynthetic process.

Bma-dmsr-8

Brugia malayi

Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Is an ortholog of C. elegans dmsr-8.

Bma-exos-8

Brugia malayi

Predicted to be involved in RNA catabolic process and RNA processing. Predicted to be part of exosome (RNase complex). Is an ortholog of C. elegans exos-8.

Bma-hlh-8

Brugia malayi

Predicted to enable protein dimerization activity. Is an ortholog of C. elegans hlh-8. In C. elegans, hlh-8 is involved in mesodermal cell fate specification; positive regulation of transcription by RNA polymerase II; and vulval cell fate specification.

Bma-hot-8

Brugia malayi

Is predicted to encode a protein with the following domains: Caenorhabditis elegans ly-6-related and Caenorhabditis elegans ly-6-related protein. Is an ortholog of C. elegans hot-8.

Bma-hpo-8

Brugia malayi

Is affected by ivermectin based on RNA-seq studies. Is predicted to encode a protein with the following domains: Protein-tyrosine phosphatase-like, PTPLA and Protein tyrosine phosphatase-like protein, PTPLA. Is an ortholog of C. elegans hpo-8.

Bma-kel-8

Brugia malayi

Is predicted to encode a protein with the following domains: Kelch-type beta propeller; Galactose oxidase/kelch, beta-propeller; Kelch motif; Kelch repeat type 1; BTB/POZ domain; BTB-kelch protein; BTB/Kelch-associated; BTB And C-terminal Kelch; and SKP1/BTB/POZ domain superfamily. Is an ortholog of C. elegans kel-8. In C. elegans, kel-8 is involved in protein ubiquitination and ubiquitin-dependent protein catabolic process.

Bma-mlst-8

Brugia malayi

Predicted to be involved in TOR signaling. Predicted to be part of TORC1 complex and TORC2 complex. Is an ortholog of C. elegans mlst-8. In C. elegans, mlst-8 is involved in mesendoderm development.