Is affected by several genes including drh-3; smgl-1; and smg-2 based on microarray and RNA-seq studies. Is affected by four chemicals including Tunicamycin; lithium chloride; and lithium carbonate based on microarray studies.
Predicted to enable glycerol-3-phosphate O-acyltransferase activity. Predicted to be involved in cellular lipid metabolic process and glycerol-3-phosphate metabolic process. Located in mitochondrion. Expressed in muscle cell. Is an ortholog of human GPAM (glycerol-3-phosphate acyltransferase, mitochondrial).
Predicted to enable GTP binding activity and GTPase activity. Involved in exocytosis; positive regulation of defecation; and positive regulation of protein catabolic process. Located in synaptic vesicle. Expressed in ALML; ALMR; BDUL; BDUR; and neurons. Human ortholog(s) of this gene implicated in Griscelli syndrome type 2 and non-Langerhans-cell histiocytosis. Is an ortholog of human RAB27A (RAB27A, member RAS oncogene family).
Predicted to enable dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity. Predicted to be involved in oligosaccharide-lipid intermediate biosynthetic process and protein N-linked glycosylation. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ic. Is an ortholog of human ALG6 (ALG6 alpha-1,3-glucosyltransferase).
Predicted to enable GTP binding activity and GTPase activity. Involved in negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process; positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process; and positive regulation of endosome to plasma membrane protein transport. Located in basolateral plasma membrane; cytoplasmic side of apical plasma membrane; and recycling endosome membrane. Expressed in several structures, including excretory cell; intestine; pharyngeal muscle cell; ventral nerve cord; and vulva. Is an ortholog of human ARF6 (ADP ribosylation factor 6).
Predicted to enable nucleosome binding activity. Predicted to be located in cytoplasm; cytoskeleton; and nucleus. Predicted to be part of Swr1 complex. Is an ortholog of human ACTR6 (actin related protein 6).