Bma-adm-4

Brugia malayi

Predicted to enable metallopeptidase activity. Is an ortholog of C. elegans adm-4. In C. elegans, adm-4 is involved in Notch signaling pathway and cell fate specification.

Bma-arx-4

Brugia malayi

Predicted to be involved in Arp2/3 complex-mediated actin nucleation and actin filament polymerization. Predicted to be located in actin cytoskeleton. Predicted to be part of Arp2/3 protein complex. Is an ortholog of C. elegans arx-4. In C. elegans, arx-4 is involved in epithelial cell migration and morphogenesis of embryonic epithelium.

Bma-attf-4

Brugia malayi

Is predicted to encode a protein with the following domain: AT hook-containing protein attf-4-like. Is an ortholog of C. elegans attf-4.

Bma-bre-4

Brugia malayi

Predicted to enable glycosyltransferase activity. Predicted to be involved in carbohydrate metabolic process. Is an ortholog of C. elegans bre-4. In C. elegans, bre-4 is involved in positive regulation of Notch signaling pathway; protein glycosylation; and response to toxic substance.

Bma-cal-4

Brugia malayi

Predicted to enable calcium ion binding activity. Is an ortholog of C. elegans cal-4.

Bma-cat-4

Brugia malayi

Predicted to enable GTP cyclohydrolase I activity. Predicted to be involved in tetrahydrofolate biosynthetic process. Is an ortholog of C. elegans cat-4. In C. elegans, cat-4 is involved in dopamine biosynthetic process from tyrosine; melanin biosynthetic process; and tetrahydrobiopterin biosynthetic process.

Bma-dnc-4

Brugia malayi

Predicted to be part of dynactin complex. Is an ortholog of C. elegans dnc-4.

Bma-ekl-4

Brugia malayi

Predicted to be involved in DNA repair; chromatin remodeling; and negative regulation of DNA-templated transcription. Predicted to be located in nucleus. Predicted to be part of NuA4 histone acetyltransferase complex. Is an ortholog of C. elegans ekl-4. In C. elegans, ekl-4 is involved in negative regulation of cell fate specification.

Bma-epg-4

Brugia malayi

Is predicted to encode a protein with the following domain: Etoposide-induced 2.4. Is an ortholog of C. elegans epg-4. In C. elegans, epg-4 is involved in macroautophagy and negative regulation of autophagosome assembly.

Bma-gei-4

Brugia malayi

Enriched in reproductive tract based on proteomic studies. Is an ortholog of C. elegans gei-4. In C. elegans, gei-4 is involved in negative regulation of Ras protein signal transduction and negative regulation of vulval development.