such-3

Caenorhabditis elegans

abt-3

Caenorhabditis elegans

Enriched in male based on RNA-seq studies. Is affected by several genes including numr-2; numr-1; and rsr-2 based on RNA-seq; tiling array; and microarray studies. Is affected by seven chemicals including Tunicamycin; manganese chloride; and multi-walled carbon nanotube based on microarray and RNA-seq studies.

acd-3

Caenorhabditis elegans

Predicted to enable ligand-gated sodium channel activity. Predicted to be involved in sodium ion transmembrane transport. Predicted to be located in plasma membrane. Expressed in intestinal cell.

adt-3

Caenorhabditis elegans

Predicted to enable metalloendopeptidase activity. Predicted to be involved in extracellular matrix organization. Predicted to be located in extracellular matrix.

aexr-3

Caenorhabditis elegans

Predicted to enable neuropeptide receptor activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in membrane.

ags-3

Caenorhabditis elegans

Enables G-protein alpha-subunit binding activity. Involved in regulation of feeding behavior. Located in membrane. Expressed in several structures, including hermaphrodite gonad; intestine; muscle cell; neurons; and tail. Human ortholog(s) of this gene implicated in sensorineural hearing loss. Is an ortholog of human GPSM1 (G protein signaling modulator 1) and GPSM2 (G protein signaling modulator 2).

algn-3

Caenorhabditis elegans

Predicted to enable dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity. Predicted to be involved in protein glycosylation. Predicted to be located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Id. Is an ortholog of human ALG3 (ALG3 alpha-1,3- mannosyltransferase).

aman-3

Caenorhabditis elegans

Predicted to enable alpha-mannosidase activity. Predicted to be involved in N-glycan processing. Predicted to be located in Golgi membrane.

asm-3

Caenorhabditis elegans

Predicted to enable acid sphingomyelin phosphodiesterase activity. Involved in lipid droplet disassembly. Predicted to be located in extracellular space and lysosome. Human ortholog(s) of this gene implicated in Niemann-Pick disease type A and Niemann-Pick disease type B. Is an ortholog of human SMPD1 (sphingomyelin phosphodiesterase 1).

bah-3

Caenorhabditis elegans

Used to study bacterial infectious disease.