acs-15

Caenorhabditis elegans

Predicted to enable long-chain fatty acid-CoA ligase activity. Predicted to be involved in long-chain fatty acid metabolic process. Predicted to be located in endoplasmic reticulum and membrane. Human ortholog(s) of this gene implicated in acute myeloid leukemia and obesity. Is an ortholog of human ACSL1 (acyl-CoA synthetase long chain family member 1) and ACSL6 (acyl-CoA synthetase long chain family member 6).

clc-15

Caenorhabditis elegans

Predicted to be located in membrane.

cox-15

Caenorhabditis elegans

Predicted to enable oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor. Predicted to be involved in heme A biosynthetic process. Predicted to be located in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in Leigh disease; hypertrophic cardiomyopathy; and mitochondrial complex IV deficiency nuclear type 6. Is an ortholog of human COX15 (cytochrome c oxidase assembly homolog COX15).

cyn-15

Caenorhabditis elegans

Predicted to enable peptidyl-prolyl cis-trans isomerase activity. Is an ortholog of human PPWD1 (peptidylprolyl isomerase domain and WD repeat containing 1).

ddx-15

Caenorhabditis elegans

Predicted to enable RNA binding activity and RNA helicase activity. Predicted to be involved in rRNA processing. Predicted to be located in nucleus. Predicted to be part of spliceosomal complex. Is an ortholog of human DHX15 (DEAH-box helicase 15).

dnj-15

Caenorhabditis elegans

Predicted to enable ATPase activator activity and protein-folding chaperone binding activity. Predicted to be involved in [2Fe-2S] cluster assembly. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in sideroblastic anemia. Is an ortholog of human HSCB (HscB mitochondrial iron-sulfur cluster cochaperone).

dyf-15

Caenorhabditis elegans

fbxa-15

Caenorhabditis elegans

Enriched in intestine and pharyngeal-intestinal valve based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including cyc-1; etr-1; and mrps-5 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including D-glucose; Zidovudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: FTH domain; F-box-like domain superfamily; F-box domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224.

grd-15

Caenorhabditis elegans

Enriched in PHso1L; arc ant V; and excretory system based on single-cell RNA-seq studies. Is affected by several genes including numr-2; numr-1; and atfs-1 based on tiling array; microarray; and RNA-seq studies. Is affected by eleven chemicals including mianserin; Zidovudine; and Psoralens based on RNA-seq studies. Is predicted to encode a protein with the following domain: Ground-like domain.

mdt-15

Caenorhabditis elegans

Enables nuclear receptor binding activity and transcription coactivator activity. Involved in several processes, including determination of adult lifespan; regulation of primary metabolic process; and sequestering of triglyceride. Predicted to be located in nucleus. Expressed in head. Used to study chromosome 22q11.2 deletion syndrome, distal. Human ortholog(s) of this gene implicated in schizophrenia. Is an ortholog of human MED15 (mediator complex subunit 15).