Ovo-aex-3

Onchocerca volvulus

Is predicted to encode a protein with the following domains: dDENN domain; cDENN domain; uDENN domain; MAP kinase-activating death domain protein; and DENN (AEX-3) domain. Is an ortholog of C. elegans aex-3. In C. elegans, aex-3 is involved in several processes, including egg-laying behavior; mating; and positive regulation of digestive system process.

Ovo-aex-6

Onchocerca volvulus

Predicted to enable GTP binding activity and GTPase activity. Is an ortholog of C. elegans aex-6. In C. elegans, aex-6 is involved in exocytosis; positive regulation of defecation; and positive regulation of protein catabolic process.

Ovo-aex-5

Onchocerca volvulus

Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Is an ortholog of C. elegans aex-5. In C. elegans, aex-5 is involved in several processes, including neuropeptide processing; positive regulation of digestive system process; and positive regulation of synaptic assembly at neuromuscular junction.

OVOC1921

Onchocerca volvulus

Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Is an ortholog of C. elegans aex-5. In C. elegans, aex-5 is involved in several processes, including neuropeptide processing; positive regulation of digestive system process; and positive regulation of synaptic assembly at neuromuscular junction.

OVOC5188

Onchocerca volvulus

Is predicted to encode a protein with the following domains: DENN (AEX-3) domain and cDENN domain. Is an ortholog of B. malayi Bm10957.

Ovo-denn-4

Onchocerca volvulus

Is predicted to encode a protein with the following domains: Tetratricopeptide-like helical domain superfamily; dDENN domain; cDENN domain; uDENN domain; and DENN (AEX-3) domain. Is an ortholog of C. elegans denn-4.

Ovo-lst-6

Onchocerca volvulus

Is predicted to encode a protein with the following domains: dDENN domain; PLAT/LH2 domain superfamily; PLAT/LH2 domain; uDENN domain; cDENN domain; RUN domain; RUN domain superfamily; and DENN (AEX-3) domain. Is an ortholog of C. elegans pkd-2. In C. elegans, pkd-2 is involved in calcium ion transport; response to hermaphrodite contact; and vulval location.

Ovo-mtm-5

Onchocerca volvulus

Is predicted to encode a protein with the following domains: Myotubularin-like phosphatase domain; Pleckstrin homology domain; Phorbol esters/diacylglycerol binding domain (C1 domain); GRAM domain; dDENN domain; PH domain; Protein-tyrosine phosphatase-like; Myotubularin protein; Protein kinase C-like, phorbol ester/diacylglycerol-binding domain; Myotubularin family; uDENN domain; cDENN domain; DENN (AEX-3) domain; PH-like domain superfamily; and SBF1/SBF2 domain. Is an ortholog of C. elegans mtm-5.