acy-1

Caenorhabditis elegans

Predicted to enable adenylate cyclase activity. Involved in several processes, including locomotory exploration behavior; memory; and regulation of defecation. Predicted to be located in plasma membrane. Expressed in body wall musculature; ganglia; neurons; ventral nerve cord; and vulval muscle. Human ortholog(s) of this gene implicated in mood disorder. Is an ortholog of human ADCY9 (adenylate cyclase 9).

acy-2

Caenorhabditis elegans

Predicted to enable adenylate cyclase activity. Involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway and nematode larval development. Predicted to be located in plasma membrane. Expressed in CANL; CANR; head ganglion; and ventral cord neurons. Is an ortholog of human ADCY2 (adenylate cyclase 2) and ADCY7 (adenylate cyclase 7).

acy-4

Caenorhabditis elegans

Predicted to enable adenylate cyclase activity. Involved in oocyte growth. Acts upstream of or within with a positive effect on oocyte maturation. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 44 and lethal congenital contracture syndrome. Is an ortholog of human ADCY6 (adenylate cyclase 6).

acy-3

Caenorhabditis elegans

Predicted to enable calcium- and calmodulin-responsive adenylate cyclase activity. Involved in negative regulation of protein kinase C signaling and regulation of establishment of cell polarity. Predicted to be located in plasma membrane.