Bm4145

Brugia malayi

Is affected by 20-hydroxyecdysone based on proteomic studies. Is predicted to encode a protein with the following domains: AMP-dependent synthetase/ligase; AMP-binding enzyme; AMP-binding enzyme, C-terminal domain; AMP-binding enzyme C-terminal domain; AMP-binding enzyme, C-terminal domain superfamily; and ANL, N-terminal domain. Is an ortholog of C. elegans acs-1 and acs-2. In C. elegans, acs-2 is involved in fatty acid metabolic process.

Bm3983

Brugia malayi

Is predicted to encode a protein with the following domains: AMP-dependent synthetase/ligase; AMP-binding enzyme; AMP-binding enzyme, C-terminal domain; AMP-binding enzyme C-terminal domain; AMP-binding enzyme, C-terminal domain superfamily; and ANL, N-terminal domain. Is an ortholog of C. elegans acs-11 and acs-21.

Bma-acs-19

Brugia malayi

Predicted to enable AMP binding activity and acetate-CoA ligase activity. Predicted to be involved in acetyl-CoA biosynthetic process from acetate. Is an ortholog of C. elegans acs-19. In C. elegans, acs-19 is involved in positive regulation of proteasomal ubiquitin-dependent protein catabolic process and regulation of response to oxidative stress.

Bma-acs-3

Brugia malayi

Is predicted to encode a protein with the following domains: ANL, N-terminal domain; AMP-dependent synthetase/ligase; and AMP-binding enzyme. Is an ortholog of C. elegans acs-3.

Bma-acs-16

Brugia malayi

Is predicted to encode a protein with the following domains: ANL, N-terminal domain; AMP-dependent synthetase/ligase; AMP-binding enzyme; and AMP-binding enzyme, C-terminal domain superfamily. Is an ortholog of C. elegans acs-16.

Bma-acs-4.2

Brugia malayi

Enriched in reproductive tract based on proteomic studies. Is predicted to encode a protein with the following domains: ANL, N-terminal domain; AMP-dependent synthetase/ligase; and AMP-binding enzyme. Is an ortholog of C. elegans acs-4.

Bma-acs-4.1

Brugia malayi

Is predicted to encode a protein with the following domains: ANL, N-terminal domain; AMP-dependent synthetase/ligase; AMP-binding enzyme; and AMP-binding enzyme, C-terminal domain superfamily. Is an ortholog of C. elegans acs-4.

Bma-acs-12

Brugia malayi

Is predicted to encode a protein with the following domains: AMP-dependent synthetase/ligase; AMP-binding enzyme; AMP-binding enzyme, C-terminal domain; AMP-binding enzyme C-terminal domain; AMP-binding enzyme, C-terminal domain superfamily; and ANL, N-terminal domain. Is an ortholog of C. elegans acs-12.

Bma-tsn-1

Brugia malayi

Predicted to be involved in regulatory ncRNA-mediated gene silencing. Predicted to be part of RNAi effector complex. Is an ortholog of C. elegans tsn-1. In C. elegans, tsn-1 is involved in miRNA-mediated post-transcriptional gene silencing.

Bma-acs-9

Brugia malayi

Is predicted to encode a protein with the following domains: AMP-dependent synthetase/ligase; AMP-binding enzyme; AMP-binding enzyme, C-terminal domain; AMP-binding enzyme C-terminal domain; AMP-binding enzyme, C-terminal domain superfamily; and ANL, N-terminal domain. Is an ortholog of C. elegans acs-9.