Enables G protein-coupled acetylcholine receptor activity. Involved in several processes, including G protein-coupled acetylcholine receptor signaling pathway; positive regulation of acetylcholine secretion, neurotransmission; and positive regulation of protein localization to synapse. Located in plasma membrane. Expressed in body wall musculature; linker cell; neurons; non-striated muscle; and somatic nervous system. Human ortholog(s) of this gene implicated in several diseases, including Chagas disease; autoimmune disease of the nervous system (multiple); and lung disease (multiple). Is an ortholog of human CHRM1 (cholinergic receptor muscarinic 1); CHRM3 (cholinergic receptor muscarinic 3); and CHRM5 (cholinergic receptor muscarinic 5).
Predicted to enable hydroxymethylglutaryl-CoA lyase activity. Predicted to be involved in L-leucine catabolic process and ketone body biosynthetic process. Human ortholog(s) of this gene implicated in amino acid metabolic disorder. Is an ortholog of human HMGCL (3-hydroxy-3-methylglutaryl-CoA lyase) and HMGCLL1 (3-hydroxy-3-methylglutaryl-CoA lyase like 1).