neg-1

Caenorhabditis elegans

Located in nucleus. Expressed in AB lineage cell; ABa; ABp; and Psub1.

sld-2

Caenorhabditis elegans

Expressed in several structures, including ABa; EMS; Psub1; Psub2; and germ line.

era-1

Caenorhabditis elegans

Located in cell cortex. Expressed in several structures, including AB; AB lineage cell; ABa; ABp; and germ line.

VC5.2

Caenorhabditis elegans

Enriched in several structures, including ABarpaapap; ABarpaappa; ABarpaappp; ABarppaapa; and body wall musculature based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including cyc-1; cyd-1; and etr-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including allantoin; Sirolimus; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: EGF-like domain; Nematode polyprotein allergen ABA-1; Laminin EGF domain; Laminin/Netrin Extracellular Matrix; Polyprotein allergen, nematode; Laminin-type EGF domain; and DVA-1 superfamily.

tres-1

Caenorhabditis elegans

Expressed in several structures, including ABa; EMS; Psub1; Psub2; and gonad. Is an ortholog of human TICRR (TOPBP1 interacting checkpoint and replication regulator). Human TICRR enables chromatin binding activity.

npa-1

Caenorhabditis elegans

Enriched in several structures, including RIF; body ganglion; germ line; head mesodermal cell; and intestine based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including cyc-1; myrf-1; and cyd-1 based on proteomic; microarray; and RNA-seq studies. Is affected by twenty-five chemicals including Astaxanthin; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Aerolysin-like pore-forming protein; Polyprotein allergen, nematode; DVA-1 superfamily; and Nematode polyprotein allergen ABA-1.

tbx-37

Caenorhabditis elegans

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in pharynx development. Located in nucleus. Expressed in head neurons. Human ortholog(s) of this gene implicated in Abruzzo-Erickson syndrome; X-linked cleft palate with or without ankyloglossia; and bone disease (multiple). Is an ortholog of several human genes including TBX15 (T-box transcription factor 15); TBX4 (T-box transcription factor 4); and TBX6 (T-box transcription factor 6).

mex-6

Caenorhabditis elegans

Enables mRNA 3'-UTR binding activity; protein domain specific binding activity; and protein kinase binding activity. Involved in regulation of protein localization. Located in P granule. Expressed in AB; ABa; ABp; and germ line.

tbx-38

Caenorhabditis elegans

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in pharynx development. Located in nucleus. Expressed in head neurons. Human ortholog(s) of this gene implicated in Abruzzo-Erickson syndrome; X-linked cleft palate with or without ankyloglossia; and bone disease (multiple). Is an ortholog of several human genes including TBX15 (T-box transcription factor 15); TBX4 (T-box transcription factor 4); and TBX6 (T-box transcription factor 6).

alh-9

Caenorhabditis elegans

Predicted to enable aldehyde dehydrogenase (NAD+) activity. Predicted to be involved in cellular aldehyde metabolic process. Expressed in ABa; RIML; RIMR; neurons; and seam cell. Human ortholog(s) of this gene implicated in early-onset vitamin B6-dependent epilepsy 4 and hepatocellular carcinoma. Is an ortholog of human ALDH7A1 (aldehyde dehydrogenase 7 family member A1).