tbx-35

Caenorhabditis elegans

Enables sequence-specific DNA binding activity. Involved in cell fate specification; chordate pharyngeal muscle development; and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of chromatin. Expressed in several structures, including MSaa; MSpa; MSpp; head neurons; and intestine.

C12D8.21

Caenorhabditis elegans

Enriched in ABalapppaa; body wall muscle cell from MS lineage; neurons; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including nuo-6; alg-1; and alh-4 based on RNA-seq and microarray studies. Is affected by Sirolimus based on microarray studies.

T05C12.15

Caenorhabditis elegans

Enriched in GABAergic neurons and body wall muscle cell from MS lineage based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including etr-1; dpl-1; and ints-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies.

F54D11.3

Caenorhabditis elegans

Enriched in ABarppaapp; ABarpppapp; body wall muscle cell from MS lineage; germ line; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including cyc-1; swsn-1; and puf-8 based on microarray; RNA-seq; and tiling array studies. Is affected by eighteen chemicals including hydrogen sulfide; methylmercuric chloride; and D-glucose based on microarray and RNA-seq studies.

E01G4.3

Caenorhabditis elegans

Enriched in several structures, including ILshVR; body wall muscle cell from MS lineage; coelomocyte; head mesodermal cell; and neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including cyc-1; cyd-1; and nuo-6 based on microarray; tiling array; and RNA-seq studies. Is affected by eighteen chemicals including rotenone; D-glucose; and stavudine based on RNA-seq and microarray studies.

ms(3)K81

Drosophila melanogaster

male sterile (3) K81 (ms(3)K81) encodes a telomere capping protein that is required to protect sperm telomeres from end-to-end fusion at fertilization. The ms(3)K81 product replaces its paralog HipHop in post-meiotic male germ cell nuclei.

K02B7.3

Caenorhabditis elegans

Enriched in several structures, including body wall muscle cell from MS lineage; excretory cell; hermaphrodite gonad; oxygen sensory neurons; and rectal epithelial cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including cyc-1; nuo-6; and ztf-11 based on microarray and RNA-seq studies. Is affected by ten chemicals including rotenone; Psoralens; and allantoin based on RNA-seq and microarray studies.

T05A7.1

Caenorhabditis elegans

Enriched in several structures, including ABplapapppp; body wall muscle cell from MS lineage; germ line; hyp12; and interfacial epithelial cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including cyc-1; cyd-1; and nuo-6 based on microarray; proteomic; tiling array; and RNA-seq studies. Is affected by sixteen chemicals including hydrogen sulfide; rotenone; and manganese chloride based on microarray and RNA-seq studies.

med-2

Caenorhabditis elegans

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in endodermal cell fate specification and pharynx development. Predicted to be located in nucleus. Expressed in E; EMS; MS; and gonad.

C27B7.9

Caenorhabditis elegans

Enriched in several structures, including body wall muscle cell from MS lineage; dopaminergic neurons; germ line; head ganglion; and hypodermis based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including fzo-1; swsn-2.2; and swsn-1 based on RNA-seq; tiling array; proteomic; and microarray studies. Is affected by twenty-one chemicals including 1-methylnicotinamide; methylmercuric chloride; and manganese chloride based on RNA-seq and microarray studies.