nkb-3

Caenorhabditis elegans

Predicted to enable ATPase activator activity. Predicted to be involved in intracellular monoatomic cation homeostasis and monoatomic cation transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of sodium:potassium-exchanging ATPase complex. Human ortholog(s) of this gene implicated in essential hypertension. Is an ortholog of several human genes including ATP1B1 (ATPase Na+/K+ transporting subunit beta 1); ATP1B2 (ATPase Na+/K+ transporting subunit beta 2); and ATP1B3 (ATPase Na+/K+ transporting subunit beta 3).

nkb-2

Caenorhabditis elegans

Predicted to enable ATPase activator activity. Predicted to be involved in intracellular monoatomic cation homeostasis and monoatomic cation transmembrane transport. Predicted to be located in membrane. Predicted to be part of sodium:potassium-exchanging ATPase complex. Human ortholog(s) of this gene implicated in several diseases, including atrophic gastritis; autoimmune gastritis; and essential hypertension. Is an ortholog of several human genes including ATP1B1 (ATPase Na+/K+ transporting subunit beta 1); ATP1B2 (ATPase Na+/K+ transporting subunit beta 2); and ATP1B3 (ATPase Na+/K+ transporting subunit beta 3).

nkb-1

Caenorhabditis elegans

Predicted to enable ATPase activator activity. Predicted to be involved in intracellular monoatomic cation homeostasis and monoatomic cation transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of sodium:potassium-exchanging ATPase complex. Expressed in neurons and non-striated muscle. Human ortholog(s) of this gene implicated in several diseases, including atrophic gastritis; autoimmune gastritis; and essential hypertension. Is an ortholog of several human genes including ATP1B1 (ATPase Na+/K+ transporting subunit beta 1); ATP1B2 (ATPase Na+/K+ transporting subunit beta 2); and ATP1B3 (ATPase Na+/K+ transporting subunit beta 3).

eat-6

Caenorhabditis elegans

Enables P-type sodium:potassium-exchanging transporter activity. Involved in action potential; monoatomic ion transport; and regulation of muscle contraction. Located in membrane. Expressed in several structures, including coelomocyte; intestine; neurons; pharynx; and vulval muscle. Used to study alcohol use disorder. Human ortholog(s) of this gene implicated in several diseases, including Charcot-Marie-Tooth disease type 2DD; alternating hemiplegia of childhood; and brain disease (multiple). Is an ortholog of human ATP1A3 (ATPase Na+/K+ transporting subunit alpha 3).

Calx

Drosophila melanogaster

Na/Ca-exchange protein (Calx) encodes a Na-Ca exchanger involved in phototransduction and response to endoplasmic reticulum stress.

Atp

Drosophila melanogaster

Na pump alpha subunit (Atpalpha) encodes an integral membrane cation antiporter protein that utilizes ATP to shuttle Na[+] and K[+] across the plasma membrane to maintain ion homeostasis.

CJA30833

Caenorhabditis japonica

Is predicted to encode a protein with the following domain: Na,K-Atpase Interacting protein.

ENA1

Saccharomyces cerevisiae

P-type ATPase sodium pump; involved in Na+ and Li+ efflux to allow salt tolerance

PPA08175

Pristionchus pacificus

Is predicted to encode a protein with the following domain: Na,K-Atpase Interacting protein.

na

Drosophila melanogaster

narrow abdomen (na) encodes an ion channel involved in circadian locomotor rhythms and touch perception.