Predicted to be involved in double-strand break repair via homologous recombination. Predicted to be part of Shu complex. Human ortholog(s) of this gene implicated in 46 XX gonadal dysgenesis and spermatogenic failure. Is an ortholog of human ZSWIM7 (zinc finger SWIM-type containing 7).
Component of Shu complex (aka PCSS complex); Shu complex also includes Psy3, Csm2, Shu1, and promotes error-free DNA repair, Shu complex mediates inhibition of Srs2p function; promotes formation of Rad51p filaments; important for both mitotic and meiotic homologous recombination, and contains a conserved SWIM domain that is necessary for both
Is predicted to encode a protein with the following domains: DAN; Cystine-knot cytokine; DAN domain; and Cystine knot, C-terminal. Is an ortholog of C. elegans F35B12.10.
Is predicted to encode a protein with the following domains: DAN; Cystine-knot cytokine; DAN domain; and Cystine knot, C-terminal. Is an ortholog of C. elegans F35B12.10.
Is predicted to encode a protein with the following domains: DAN; Cystine-knot cytokine; DAN domain; and Cystine knot, C-terminal. Is an ortholog of C. elegans flr-2.
Subunit of the Shu complex (aka PCSS complex); Shu complex also includes Psy3, Shu1, Shu2, and promotes error-free DNA repair; Shu complex mediates inhibition of Srs2p anti-recombinase function; promotes formation of Rad51p filaments; Psy3p and Csm2p contain similar DNA-binding regions which work together to form a single DNA binding site; required for accurate chromosome segregation during meiosis
Is predicted to encode a protein with the following domains: DAN; Cystine-knot cytokine; DAN domain; and Cystine knot, C-terminal. Is an ortholog of C. elegans F35B12.10.
Is predicted to encode a protein with the following domains: DAN; Cystine-knot cytokine; DAN domain; and Cystine knot, C-terminal. Is an ortholog of C. elegans F35B12.10.