CIR2

Saccharomyces cerevisiae

Putative ortholog of human ETF-dH; found in a large supramolecular complex with other mitochondrial dehydrogenases; may have a role in oxidative stress response; ETF-dH is also known as electron transfer flavoprotein dehydrogenase

CBN08501

Caenorhabditis brenneri

Is predicted to encode a protein with the following domain: Dbl homology (DH) domain superfamily.

CJA34038

Caenorhabditis japonica

Is predicted to encode a protein with the following domain: Dbl homology (DH) domain superfamily.

CBN02634

Caenorhabditis brenneri

Is predicted to encode a protein with the following domains: Dbl homology (DH) domain superfamily and PH-like domain superfamily.

TMUE_1000002677

Trichuris muris

Is predicted to encode a protein with the following domains: Dbl homology (DH) domain superfamily and PH-like domain superfamily.

TMUE_1000002718

Trichuris muris

Is predicted to encode a protein with the following domains: Dbl homology (DH) domain superfamily and PH-like domain superfamily.

CJA41661

Caenorhabditis japonica

Is predicted to encode a protein with the following domain: Dbl homology (DH) domain superfamily. Is an ortholog of C. elegans tag-77.

Rmi2

Homo sapiens

RMI2 is a component of the BLM (RECQL3; MIM 604610) complex, which plays a role in homologous recombination-dependent DNA repair and is essential for genome stability (Xu et al., 2008 [PubMed 18923082]).[supplied by OMIM, Nov 2008]

Acer2

Homo sapiens

The sphingolipid metabolite sphingosine-1-phosphate promotes cell proliferation and survival, whereas its precursor, sphingosine, has the opposite effect. The ceramidase ACER2 hydrolyzes very long chain ceramides to generate sphingosine (Xu et al., 2006 [PubMed 16940153]).[supplied by OMIM, Jul 2010]

Slc9a8

Homo sapiens

Sodium-hydrogen exchangers (NHEs), such as SLC9A8, are integral transmembrane proteins that exchange extracellular Na+ for intracellular H+. NHEs have multiple functions, including intracellular pH homeostasis, cell volume regulation, and electroneutral NaCl absorption in epithelia (Xu et al., 2008 [PubMed 18209477]).[supplied by OMIM, Apr 2009]