ckc-1

Caenorhabditis elegans

Predicted to enable ethanolamine kinase activity. Predicted to be involved in phosphatidylethanolamine biosynthetic process. Predicted to be located in cytoplasm. Is an ortholog of human ETNK2 (ethanolamine kinase 2).

ghi-1

Caenorhabditis elegans

Predicted to enable lipid binding activity.

pcaf-1

Caenorhabditis elegans

Predicted to enable histone H3 acetyltransferase activity. Predicted to be involved in chromatin remodeling and positive regulation of transcription by RNA polymerase II. Predicted to be located in centrosome and nucleus. Predicted to be part of ATAC complex. Human ortholog(s) of this gene implicated in breast cancer; carcinoma (multiple); and rheumatoid arthritis. Is an ortholog of human KAT2A (lysine acetyltransferase 2A).

sul-1

Caenorhabditis elegans

Enables heparan sulfate 6-O-sulfotransferase activity. Involved in heparan sulfate proteoglycan biosynthetic process, enzymatic modification. Predicted to be located in Golgi stack; cell surface; and endoplasmic reticulum. Is an ortholog of human SULF1 (sulfatase 1) and SULF2 (sulfatase 2).

fcho-1

Caenorhabditis elegans

Involved in clathrin-dependent endocytosis. Located in plasma membrane. Expressed in amphid neurons; hypodermis; intestine; pharyngeal cell; and rectal gland cell. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Is an ortholog of human FCHO2 (FCH and mu domain containing endocytic adaptor 2).

Syngr

Drosophila melanogaster

Synaptogyrin (Syngr) encodes a synaptic vesicle protein implicated in vesicle endocytosis during the bulk endocytosis process. It is the sole Drosopohila homolog of the synaptophysin/synaptogryin synaptic vesicle family of proteins.

tol-1

Caenorhabditis elegans

Predicted to enable signaling receptor activity. Involved in defense response to Gram-negative bacterium and embryo development. Predicted to be located in extracellular matrix and extracellular space. Expressed in neurons. Is an ortholog of several human genes including CHAD (chondroadherin); ELFN2 (extracellular leucine rich repeat and fibronectin type III domain containing 2); and TRIL (TLR4 interactor with leucine rich repeats).

TOG1

Saccharomyces cerevisiae

Transcriptional activator of oleate genes; regulates genes involved in fatty acid utilization; zinc cluster protein; deletion confers sensitivity to Calcufluor white, and prevents growth on glycerol or lactate as sole carbon source

CHA1

Saccharomyces cerevisiae

Catabolic L-serine (L-threonine) deaminase; catalyzes the degradation of both L-serine and L-threonine; required to use serine or threonine as the sole nitrogen source, transcriptionally induced by serine and threonine

PUT1

Saccharomyces cerevisiae

Proline oxidase; nuclear-encoded mitochondrial protein involved in utilization of proline as sole nitrogen source; PUT1 transcription is induced by Put3p in the presence of proline and the absence of a preferred nitrogen source